8 results for "Actin-related Products" in Products
Actin-related Products Products
Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is found in two main states: G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both G- and F-actin are intrinsically flexible structures - a feature vital in actin's role as a dynamic filament network.
Actin has four major functions. Firstly, F-actin polymers form microfilaments - polar intracellular 'tracks' for kinesin motor proteins, allowing the ...
Disrupts actin filament function
| Alternate Names: | Zygosporin A |
| Chemical Name: | (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione |
| Purity: | ≥95% (HPLC) |
Inhibitor of actin assembly and polymerization
| Alternate Names: | LAT-A |
| Chemical Name: | 4-[(1R,4Z,8E,10Z,12S,15R, 17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone |
| Purity: | ≥95% (HPLC) |
Inhibitor of actin polymerization
| Chemical Name: | (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone |
| Purity: | ≥95% (HPLC) |
Inhibitor of actin polymerization
| Chemical Name: | (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione |
| Purity: | ≥98% (HPLC) |
Stabilizes F-actin; promotes actin polymerization
| Chemical Name: | Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl] |
| Purity: | ≥97% (HPLC) |
Promotes actin polymerization
| Purity: | ≥90% (HPLC) |
N-WASP inhibitor; inhibits Arp2/3 activation
| Chemical Name: | 3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol |
| Purity: | ≥98% (HPLC) |
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression
| Chemical Name: | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
| Purity: | ≥98% (HPLC) |
