Cytochalasin B

Tocris Bioscience, part of Bio-Techne | Catalog # 5474

Inhibitor of actin polymerization
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Key Product Details

Description

Inhibitor of actin polymerization

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Product Description

Cytochalasin B is an inhibitor of actin polymerization. Inhibits cell division, migration and glucose transport. Causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells. Cell permeable.

Product Specifications

Molecular Weight

479.61

Formula

C29H37NO5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione

CAS Number

14930-96-2

PubChem ID

5311281

InChI Key

GBOGMAARMMDZGR-TYHYBEHESA-N

SMILES

C=C([C@H]1C)[C@@H](O)[C@]([C@@]2(O3)[C@]1([H])[C@H](CC4=CC=CC=C4)NC2=O)([H])/C=C/C[C@H](C)CCC[C@@H](O)/C=C/C3=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 4.8 10 with gentle warming

Preparing Stock Solutions for Cytochalasin B

The following data is based on the product molecular weight 479.61

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.85 mL 104.25 mL 208.50 mL
0.5 mM 4.17 mL 20.85 mL 41.70 mL
1 mM 2.09 mL 10.43 mL 20.85 mL
5 mM 0.42 mL 2.09 mL 4.17 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Cytochalasin B

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cytochalasin B

For research use only

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