Phalloidin
Tocris Bioscience, part of Bio-Techne | Catalog # 4535
Promotes actin polymerization
Product Description
Phalloidin is a promotes actin polymerization. Decreases dissociation rate constant for actin subunits from filament ends; lowers critical concentration for polymerization.Product Specifications
Molecular Weight
788.87
Formula
C35H48N8O11S
Storage
Store at -20°C
Purity
≥90% (HPLC)
CAS Number
17466-45-4
PubChem ID
90488951
InChI Key
KPKZJLCSROULON-RCGKFKHASA-N
SMILES
O=C([C@H](N5)CSC(NC3=C2C=CC=C3)=C2C[C@@H](C(N[C@@H](C[C@](O)(C)CO)C(NC(C(N[C@H]([C@H](C)O)C5=O)=O)C)=O)=O)NC([C@@H](N[C@]4=O)C)=O)N1[C@H]4C[C@@H](O)C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wehland Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth. Proc.Natl.Acad.Sci.USA 1977 PMID: 341163
- Cooper Effects of cytochalasin and phalloidin on actin. J.Cell Biol. 1987 PMID: 3312229
- Coluccio and Tilney Phalloidin enhances actin assembly by preventing monomer dissociation. J.Cell Biol. 1984 PMID: 6746738
- Diensthuber Phalloidin perturbs the interaction of human non-muscle myosin isoforms 2A and 2C1 with F-actin. FEBS Lett. 2011 PMID: 21295570
Product Specific Notices for Phalloidin
For research use only
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