Sign In / Register
ACE-2 Products
Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.
ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. Binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.
122 results for "ACE-2" in Products
Search
Application
Product Action
Conjugates
Clonality
Host Species
Isotype
Low Endotoxin
Sample Size
Citations
Reviews
ACE-2 Products
Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.
ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. Binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.
122 results for "ACE-2" in Products
| Source : | NS0 |
| Accession # : | Q9BYF1 |
| Applications : | Bioactivity, Enzyme Activity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Simple Western, Western Blot |
Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor
| Chemical Name : | N-[(1S)-1-Carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-L-histidine |
| Purity : | ≥98% (HPLC) |
HIF-PH inhibitor; erythropoietic
| Alternate Names : | FG 4592 |
| Chemical Name : | N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine |
| Purity : | ≥98% (HPLC) |
Potent vasoconstrictor peptide
| Purity : | ≥95% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #535919 |
| Applications : | Flow Cytometry |
| Assay Range : | 0.313 - 20 ng/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Simple Western, Western Blot |
| Source : | NS0 |
| Accession # : | Q9BYF1.2 |
| Applications : | Bioactivity |
Non-peptide, competitive angiotensin-converting enzyme (ACE) inhibitor
| Chemical Name : | (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #171607 |
| Applications : | Flow Cytometry |
Pan-histone deacetylase inhibitor
| Chemical Name : | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity : | ≥98% (HPLC) |
Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling
| Chemical Name : | 2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #171606 |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #535919 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #535919 |
| Applications : | Flow Cytometry |
Biotinylated via Amines
| Source : | NS0 |
| Accession # : | Q9BYF1.2 |
| Applications : | Bioactivity, Enzyme Activity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry |
| Source : | NS0 |
| Accession # : | NP_001012006 |
| Applications : | Enzyme Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #535919 |
| Applications : | Flow Cytometry |
