ACE-2 Products
Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.
ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. The binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.
Products:
769 results for "ACE-2" in Products
769 results for "ACE-2" in Products
ACE-2 Products
Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.
ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. The binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.
Products:
| Reactivity: | Human, Mouse, Rat, Hamster |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, IP, +1 More |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/6788R |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/6788R |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human, Hamster |
| Details: | Mouse IgG2a Monoclonal Clone #171606 |
| Applications: | WB, IHC |
Analyzed by SEC-MALS
| Source: | NS0 |
| Accession #: | Q9BYF1 |
| Applications: | BA, EnzAct |
Potent vasoconstrictor peptide
| Purity: | ≥95% (HPLC) |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, ELISA, Flow, IHC, +1 More |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat, Hamster, Primate - Macaca mulatta (Rhesus Macaque) |
| Details: | Rabbit IgG Monoclonal Clone #SN0754 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Rat, Hamster |
| Details: | Mouse IgG2a Monoclonal Clone #535919 |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #AC384 |
| Applications: | WB, ELISA, Flow, B/N |
| Assay Range: | 0.313 - 20 ng/mL |
| Applications: | ELISA |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2818I |
| Applications: | WB, Flow, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Rat, Hamster |
| Details: | Mouse IgG2a Monoclonal Clone #171608 |
| Applications: | WB, IHC, IP |
Bioactive, High Spike RBD Binding
| Source: | CHO |
| Accession #: | Q9BYF1.2 |
| Applications: | BA, EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #AC18F |
| Applications: | WB, ELISA, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #535919 |
| Applications: | Flow |
Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction
| Purity: | ≥95% (HPLC) |
Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor
| Chemical Name: | N-[(1S)-1-Carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-L-histidine |
| Purity: | ≥98% (HPLC) |