Skip to main content

ACE-2: Proteins and Enzymes

Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.

ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. Binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.

16 results for "ACE-2 Proteins and Enzymes" in Products

ACE-2: Proteins and Enzymes

Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.

ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. Binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.

16 results for "ACE-2 Proteins and Enzymes" in Products

BA
BA, EnzAct

Biotinylated via Amines

Catalog #: 4516-ZN
EnzAct
BA, EnzAct

Bioactive, High Spike RBD Binding

EnzAct

HEK293 Expressed

BA, EnzAct
BA, EnzAct

Biotinylated

BA, EnzAct

Biotinylated

BA, EnzAct
EnzAct

View All of the Proteins for Coronavirus Research View Products

BA, EnzAct
EnzAct
EnzAct
Results Per Page
5 10 25 50
/ 1