Recombinant Human ACE-2 Protein, CF
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | NS0 |
Accession #: | Q9BYF1 |
Structure / Form: | Recombinant Human ACE‑2 is prone to proteolytic cleavage at C-terminus. |
Applications: | Bioactivity, Enzyme Activity |
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Citations for Recombinant Human ACE-2 Protein, CF (24)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human ACE-2 Protein, CF include:
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Sample Types: Recombinant Protein
Applications: BioassayM Haddad et al. (2022), Molecular Interactions of Tannic Acid with Proteins Associated with SARS-CoV-2 Infectivity International Journal of Molecular Sciences, 23(5).
PMID: 35269785 -
Species: Human
Sample Types: Protein
Applications: BioassayJW Kim et al. (2022), Development and Characterization of Phage-Display-Derived Novel Human Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Biomedicines, 10(12).
PMID: 36552031 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayB Bhargavan et al. (2022), SARS-CoV-2 Spike Proteins and Cell-Cell Communication Inhibits TFPI and Induces Thrombogenic Factors in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for COVID-19 Coagulopathy Pathogenesis International Journal of Molecular Sciences, 23(18).
PMID: 36142345 -
Species: Human
Sample Types: Protein
Applications: BioassayX Guo et al. (2022), Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2 Nature Communications, 13(1):7907.
PMID: 36564389 -
R Reindl-Sch et al. (2022), The systemic renin-angiotensin system in COVID-19 Scientific Reports, 12(1):20117.
PMID: 36418458 -
Species: Human
Sample Types: Protein
Applications: BioassayY Polak et al. (2021), Metabolism of angiotensin peptides by angiotensin converting enzyme 2 (ACE2) and analysis of the effect of excess zinc on ACE2 enzymatic activity Peptides, 137(0):170477.
PMID: 33400951 -
Species: Human
Sample Types: Recombinant Protein
Applications: BioassaySP Shukla et al. (2021), "Molecular Masks" for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus Entry International Journal of Molecular Sciences, 22(16).
PMID: 34445669 -
Species: Human
Sample Types: Recombinant Protein
Applications: BioassayT Yamaguchi et al. (2021), ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury Nature Communications, 12(1):6791.
PMID: 34815389 -
Applications: Enzyme AssayJ Lu et al. (2020), High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity bioRxiv, 0(0).
PMID: 32637947 -
Species: Canine
Sample Types: Plasma
Applications: BioassayÉ Larouche-L et al. (2020), Effect of angiotensin receptor blockers and angiotensin converting enzyme?2 on plasma equilibrium angiotensin peptide concentrations in dogs with heart disease Journal of veterinary internal medicine, 0(0).
PMID: 33368659 -
Species: Feline
Sample Types: Plasma
Applications: Cell CultureT Huh et al. (2020), Effect of angiotensin receptor blockers and angiotensin-converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in cats with heart disease J Vet Intern Med, 0(0).
PMID: 33135833 -
Species: Human
Sample Types: Protein
Applications: Reference StandardJ Song et al. (2020), Physiological cyclic stretch up-regulates angiotensin-converting enzyme 2 expression to reduce proliferation and migration of vascular smooth muscle cells Biosci. Rep., 40(6).
PMID: 32463098 -
Species: Canine
Sample Types: Plasma
Applications: BioassayÉ Larouche-L et al. (2019), Plasma and tissue angiotensin-converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease J. Vet. Intern. Med., 0(0).
PMID: 31254308 -
Species: Canine
Sample Types: Plasma
Applications: BioassayÉ Larouche-L et al. (2019), Plasma and tissue angiotensin-converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease J. Vet. Intern. Med., 0(0).
PMID: 31254308 -
Species: Human
Sample Types: Urine
Applications: BioassayAM South et al. (2018), Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm J. Pediatr., 0(0).
PMID: 30404738 -
Species: Human
Sample Types: Fluorogenic Peptide Substrate
Applications: Enzyme Assay(2016), Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-? and tau pathology Alzheimers Res Ther, 8(1):50.
PMID: 27884212 -
Species: Human
Sample Types: Protein
Applications: BioassayHeurich A et al. (2014), TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein. J Virol, 88(2):1293-307.
PMID: 24227843 -
Species: Virus
Sample Types: Virus
Applications: Binding AssayZhou Y et al. (2011), A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms. J. Virol., 84(17):8753-64.
PMID: 20573835 -
Species: N/A
Sample Types: Fluorogenic Peptide Substrate
Applications: Enzyme AssayEpelman S et al. (2008), Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone system. J. Am. Coll. Cardiol., 52(9):750-4.
PMID: 18718423 -
Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Whole Cells
Applications: Bioassayde Lang A et al. (2006), Interferon-gamma and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells. Virology, 353(2):474-81.
PMID: 16860835 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryFollis KE et al. (2006), Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry. Virology, 350(2):358-69.
PMID: 16519916 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoImai Y et al. (2005), Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature, 436(7047):112-6.
PMID: 16001071 -
Species: Human
Sample Types: Whole Cells
Tai W et al. (0), Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine. Cell Mol Immuno17(6):613-620.
PMID: 32203189 -
Species: Human
Sample Types: Recombinant Protein
Applications: BioassayLu J et al. (0), High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity. J Biol Che295(52):18579-18588.
PMID: 33122196
There are no citations that match your criteria.
Customer Reviews for Recombinant Human ACE-2 Protein, CF (5)
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Application: Enzymatic activity in vitroReason for Rating: Very consistent results for enzymatic assay using either the fluorescent substrate Mca-APK(Dnp) or Angiotensin II.Verified Customer | Posted 08/24/2021
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 11/21/2020
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Application: Enzymatic activity in vitroVerified Customer | Posted 10/23/2020
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Verified Customer | Posted 08/05/2016
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Verified Customer | Posted 08/05/2016
There are no reviews that match your criteria.