Mca-YVADAPK(Dnp)-OH Fluorogenic Peptide Substrate

Citations are publications that use Bio-Techne products. Selected citations for Mca-YVADAPK(Dnp)-OH Fluorogenic Peptide Substrate include:

• Species: Human
  Sample Types: Peptides
  Applications: Bioassay

  WG Liang et al. (2022), Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition Nature Communications, 13(1):1833.
  PMID:  35383169
• Species: Human
  Sample Types: Recombinant Protein
  Applications: Bioassay

  JA Torchia et al. (2022), Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo Science Advances, 8(49):eabq6527.
  PMID:  36475798
• Species: Human
  Sample Types: Recombinant Protein
  Applications: Bioassay

  SP Shukla et al. (2021), "Molecular Masks" for ACE2 to Effectively and Safely Block SARS-CoV-2 Virus Entry International Journal of Molecular Sciences, 22(16).
  PMID:  34445669
• Species: Human
  Sample Types: Cell Lysates
  Applications: Hydrolysis Assay

  GM Castiglion et al. (2021), Evolutionary pathways to SARS-CoV-2 resistance are opened and closed by�epistasis acting on ACE2 PloS Biology, 19(12):e3001510.
  PMID:  34932561
• 
  
  Applications: Enzyme Assay

  J Lu et al. (2020), High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity bioRxiv, 0(0).
  PMID:  32637947
• Species: Human
  Sample Types: Protein
  Applications: Bioassay

  KY Huang et al. (2020), Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection EMBO Mol Med, 0(0):e12828.
  PMID:  33159417
• Species: Mouse
  Sample Types: Cells
  Applications: enzyme activity

  K Hao et al. (2019), LncRNA-Safe contributes to cardiac fibrosis through Safe-Sfrp2-HuR complex in mouse myocardial infarction Theranostics, 9(24):7282-7297.
  PMID:  31695768
• Species: Human
  Sample Types: Tissue Homogenates
  

  E Schrom et al. (2017), Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA Mol Ther Nucleic Acids, 7(0):350-365.
  PMID:  28624211
• Species: Human
  Sample Types: Plasma
  Applications: Enzyme Assay

  Putko B et al. (2014), Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology. PLoS ONE, 9(6):e99495.
  PMID:  24923671
• Species: Mouse
  Sample Types: Tissue Homogenates
  Applications: Enzyme Assay

  Qiu Y et al. (2014), Angiotensin-converting enzyme 2 (ACE2) activator diminazene aceturate ameliorates endotoxin-induced uveitis in mice. Invest Ophthalmol Vis Sci, 55(6):3809-18.
  PMID:  24854854
• Species: Mouse
  Sample Types: Tissue Homogenates
  

  Riquelme C et al. (2014), ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis. PLoS ONE, 9(4):e93449.
  PMID:  24695436
• Species: Human
  Sample Types: Cell Lysates
  Applications: Bioassay

  Yan et al. (2013), Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes. PLoS ONE, 8(11):e80029.
  PMID:  24244599
• Species: Rat
  Sample Types: Whole Tissue
  Applications: Bioassay

  Bhatia et al. (2013), Sex differences in angiotensin-converting enzyme modulation of Ang (1-7) levels in normotensive WKY rats. Am J Hypertens, 26(5):591-8.
  PMID:  23547034
• Species: Human
  
  Applications: Bioassay

  Tsuchiya S et al. (2010), Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp). J. Bone Miner. Res., 26(0):220.
  PMID:  20687161
• Species: Mouse
  Sample Types: Tissue Homogenates
  Applications: Enzyme Assay

  Park S et al. (2010), Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am. J. Physiol. Renal Physiol., 298(1):F37-48.
  PMID:  19846569
• Species: Human
  Sample Types: Recombinant Protein
  Applications: Enzyme Assay Substrate

  Bergin DA et al. (2008), Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway. J. Biol. Chem., 283(46):31736-44.
  PMID:  18772136
• Species: Human
  Sample Types: Cell Culture Supernates
  

  Lovren F et al. (2008), Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am. J. Physiol. Heart Circ. Physiol., 295(4):H1377-84.
  PMID:  18660448
• Species: Human
  Sample Types: Peptide
  Applications: Bioassay

  Lu J et al. (0), High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity. J Biol Che295(52):18579-18588.
  PMID:  33122196

There are no citations that match your criteria.

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• Mca-YVADAPK(Dnp)-OH Fluorogenic Peptide Substrate

  Name: Anonymous
  Application: Enzymatic activity in vitro
  Verified Customer | Posted 12/04/2020
  

• Mca-YVADAPK(Dnp)-OH Fluorogenic Peptide Substrate

  Name: Shrinidh Joshi
  Verified Customer | Posted 08/04/2016
  ACE-2 activity was determined following incubation with intramolecularly quenched synthetic ACE-2 specific substrate 7-Mca-YVADAPK (Dnp) (R&D systems). In the case of cell lysates, 10 µg of total protein was assayed for activity in a buffer with the following composition: 50 mM MES (4-morpholineethanesulphonic acid), 300 mM NaCl, 10 µm ZnCl2 and 0.01% Triton X-100, pH 6.5. Reaction was initiated by the addition of 5×10−5 M substrate. Where applicable, recombinant enzymes were used at a concentration of 0.01 µg per reaction. The fluorescence measurements were performed in the black microtiter plates (Costar) in a total volume of 100 µl. The plates were read using a fluorescence plate reader SpectraMax M5 (Molecular Devices) at an excitation wavelength 320 nm and emission wavelength 405 nm Fluorescence resulting from the substrate hydrolysis increased with time, and achieved maximum by one h with recombinant enzyme.
  

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