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5-HT4 Products

5HT4R, also known as HTR4, is an approximately 45 kDa multipass serotonin receptor that is expressed in the brain, gastrointestinal tract, bladder, vascular endothelial cells, atrium, kidney, and adrenal gland. It is involved in the regulation of learning, memory, anxiety, smooth muscle contraction, and adrenal corticosteroid secretion. Alternate splicing of human 5HT4R generates multiple isoforms with either a 14 aa insertion in the second extracellular loop or a deletion or various substitutions in the C-terminal cytoplasmic region. Different isoforms show tissue specific expression patterns or increased activity in the absence of ligand. Human 5HT4R shares 94% and 88% aa sequence identity with mouse and rat 5HT4R, respectively.

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108 results for "5-HT4" in Products

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5-HT4 Products

5HT4R, also known as HTR4, is an approximately 45 kDa multipass serotonin receptor that is expressed in the brain, gastrointestinal tract, bladder, vascular endothelial cells, atrium, kidney, and adrenal gland. It is involved in the regulation of learning, memory, anxiety, smooth muscle contraction, and adrenal corticosteroid secretion. Alternate splicing of human 5HT4R generates multiple isoforms with either a 14 aa insertion in the second extracellular loop or a deletion or various substitutions in the C-terminal cytoplasmic region. Different isoforms show tissue specific expression patterns or increased activity in the absence of ligand. Human 5HT4R shares 94% and 88% aa sequence identity with mouse and rat 5HT4R, respectively.

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108 results for "5-HT4" in Products

Endogenous 5-HT receptor agonist

Potent 5-HT4 agonist

Flow, IHC

Potent and selective 5-HT4 antagonist; active in vivo

5-HT4 agonist; stimulates intestinal ACh release

Catalog #: FAB6545G
Flow
Catalog #: FAB6545N
Flow
IP, WB

Potent and selective 5-HT4 antagonist

5-HT4 antagonist

5-HT4 antagonist

Highly potent 5-HT3 antagonist; also 5-HT4 agonist

Catalog #: FAB6545T
Flow
Catalog #: FAB6545U
Flow
Catalog #: FAB6545R
Flow
Catalog #: FAB6545V
Flow
Catalog #: FAB6545S
Flow
Catalog #: RDC0248

α partial agonist; also D2-like partial agonist and 5-HT antagonist

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Catalog #: NBP1-78403PEP
AC
AP, ELISA, MA, WB
IHC
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