Potent and selective 5-HT4 antagonist
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Key Product Details
Description: | Potent and selective 5-HT4 antagonist |
Chemical Name: | 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 393.5 |
Citations for GR 113808 (5)
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Citations are publications that use Bio-Techne products. Selected citations for GR 113808 include:
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Sengupta et al.
(2014)
Visceral analgesic effect of 5-HT(4) receptor agonist in rats involves the rostroventral medulla (RVM).
Neuropharmacology.
79:345
PMID: 24334068 -
Mondal et al.
(2013)
Mechanism of ghrelin-induced gastric contractions in Suncus murinus (house musk shrew): involvement of intrinsic primary afferent neurons.
PLoS One.
8:e60365
PMID: 23565235 -
Beattie et al.
(2011)
The Pharmacology of TD-8954, a Potent and Selective 5-HT(4) Receptor Agonist with Gastrointestinal Prokinetic Properties.
Front Pharmacol.
2:25
PMID: 21687517 -
Ptak et al.
(2009)
Raphé neurons stimulate respiratory circuit activity by multiple mechanisms via endogenously released serotonin and substance P.
PLoS One.
29:3720
PMID: 19321769 -
Hampson et al.
(2007)
Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs.
Diabetologia.
50:1743
PMID: 17579833
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