9 results for "5-HT1F Small Molecules and Peptides" in Products
5-HT1F Small Molecules and Peptides
5-HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Serotonin 5-HT1F receptors are located primarily in the hippocampus, cortex and dorsal raphe nucleus. Abnormal function of the serotonergic system has been implicated in a variety of neurologic and psychiatric diseases. 5-HT1F may play a role in these diseases.
Potent and selective 5-HT1F agonist
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist
5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7
High affinity D2 antagonist
Selective 5-HT3 antagonist
5-HT1A, 5-HT1B and 5-HT1D agonist
Dopamine receptor antagonist; antipsychotic
Potent 5-HT1B/1D/1F agonist
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
