Zolmitriptan

Tocris Bioscience, part of Bio-Techne | Catalog # 4657

Potent 5-HT1B/1D/1F agonist
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Key Product Details

Description

Potent 5-HT1B/1D/1F agonist

View all 5-HT1D Receptor Agonists »

Product Description

Zolmitriptan is a potent 5-HT1B/1D/1F agonist (Ki values are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1B and h5-HT1F receptors respectively). Inhibits trigeminal nerve stimulation-mediated neurogenic plasma protein extravasation in guinea pigs; blocks long excitatory postsynaptic potentials (EPSPs) in a rat model of spinal cord injury.

Product Specifications

Molecular Weight

287.36

Formula

C16H21N3O2

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

(4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone

CAS Number

139264-17-8

PubChem ID

60857

InChI Key

ULSDMUVEXKOYBU-ZDUSSCGKSA-N

SMILES

CN(C)CCC2=CNC1=CC=C(C[C@H](N3)COC3=O)C=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.74 100
Ethanol 28.74 100

Preparing Stock Solutions for Zolmitriptan

The following data is based on the product molecular weight 287.36

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.48 mL 17.40 mL 34.80 mL
5 mM 0.70 mL 3.48 mL 6.96 mL
10 mM 0.35 mL 1.74 mL 3.48 mL
50 mM 0.07 mL 0.35 mL 0.70 mL

Calculators

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Product Documents for Zolmitriptan

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Zolmitriptan

For research use only

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