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Thrombospondin-1 Products
Thrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells (EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP). TSP-1 dampens adaptive immune responses by inducing the differentiation of regulatory T cells and inhibiting TCR signaling. In the nervous system, it promotes excitatory synapse formation and supports the integration of neural progenitor cells into the olfactory bulb.
18 results for "Thrombospondin-1" in Products
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Thrombospondin-1 Products
Thrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells (EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP). TSP-1 dampens adaptive immune responses by inducing the differentiation of regulatory T cells and inhibiting TCR signaling. In the nervous system, it promotes excitatory synapse formation and supports the integration of neural progenitor cells into the olfactory bulb.
18 results for "Thrombospondin-1" in Products
Catalog #:
ARY012
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ELISA
| Sensitivity : | 0.944 ng/mL |
| Assay Range : | 7.81 - 500 ng/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Saliva, Human Milk) |
| Applications : | ELISA |
Catalog #:
7859-TH
BA
| Source : | NS0 |
| Accession # : | NP_035710 |
| Applications : | Bioactivity |
Catalog #:
ARY019
Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies
BA
| Source : | NS0 |
| Accession # : | P07996-1 |
| Applications : | Bioactivity |
WB, IP
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #301221 |
| Applications : | ELISA Capture, Immunoprecipitation, Western Blot |
Catalog #:
BAF3074
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
WB, Simple Western, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Simple Western, Western Blot |
Catalog #:
SPCKB-PS-000531
Simple Plex Cartridge Kit for quantitation of Thrombospondin-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
ELISA
| Assay Range : | 1.56 - 100 ng/mL |
| Applications : | ELISA |
Catalog #:
MAB7859
ELISA
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #899631R |
| Applications : | ELISA |
Catalog #:
MAB78591
ELISA
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #899642R |
| Applications : | ELISA |
