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Thrombospondin-1 Products

Thrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells (EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP). TSP-1 dampens adaptive immune responses by inducing the differentiation of regulatory T cells and inhibiting TCR signaling. In the nervous system, it promotes excitatory synapse formation and supports the integration of neural progenitor cells into the olfactory bulb.

18 results for "Thrombospondin-1" in Products

Thrombospondin-1 Products

Thrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells (EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP). TSP-1 dampens adaptive immune responses by inducing the differentiation of regulatory T cells and inhibiting TCR signaling. In the nervous system, it promotes excitatory synapse formation and supports the integration of neural progenitor cells into the olfactory bulb.

18 results for "Thrombospondin-1" in Products

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

BA

Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies

WB, IP
WB
WB, Simple Western, IHC

Simple Plex Cartridge Kit for quantitation of Thrombospondin-1. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Catalog #: MAB7859
ELISA

Recombinant Monoclonal Antibody.

Catalog #: MAB78591
ELISA

Recombinant Monoclonal Antibody.

Catalog #: QC170
ELISA, Ctrl

For use with catalog number DTSP10

Catalog #: 898229

Control for use with Human Thrombospondin-1 Simple Plex Cartridge Kit

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