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8 results for "SLC6A3/DAT1 Small Molecules and Peptides" in Products

SLC6A3/DAT1: Small Molecules and Peptides

The dopamine transporter (DAT) is a 70 - 80 kDa member of the Na+-neurotransmitter symporter family of transmembrane (TM) proteins. DAT plays a crucial role in the synaptic clearance of dopamine (DA). It mediates the uptake of dopamine by the presynaptic terminal, thus limiting the strength of the dopamingeric response. One molecule of DA is accompanied by two Na+ and one Cl- ion. Molecules such as amphetamine both competitively inhibit DA uptake, and induce DA release through the DAT, ...

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Selective DA uptake inhibitor; also σ ligand

Chemical Name: 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Purity: ≥98% (HPLC)
Selective DA uptake inhibitor; also σ ligand

Potent and selective DA uptake inhibitor

Chemical Name: 1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride
Purity: ≥98% (HPLC)
Potent and selective DA uptake inhibitor

Potent noradrenalin and dopamine uptake inhibitor. Antidepressant

Chemical Name: 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate
Purity: ≥98% (HPLC)
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant

5-HT reuptake inhibitor

Chemical Name: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
Purity: ≥98% (HPLC)
5-HT reuptake inhibitor

Non-selective inhibitor of dopamine and noradrenalin transporters

Chemical Name: 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride
Purity: ≥98% (HPLC)
Non-selective inhibitor of dopamine and noradrenalin transporters

Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake

Chemical Name: (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride
Purity: ≥98% (HPLC)
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake

Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake

Alternate Names: Lu 19-005
Chemical Name: (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine hydrochloride
Purity: ≥98% (HPLC)
Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake

High affinity dopamine uptake inhibitor

Chemical Name: (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride
Purity: ≥98% (HPLC)
High affinity dopamine uptake inhibitor
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