GBR 12783 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0513

Potent and selective DA uptake inhibitor
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0513/50
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Key Product Details

Description

Potent and selective DA uptake inhibitor

View all Dopamine Transporter Inhibitors »

Product Description

GBR 12783 dihydrochloride is a very potent and selective inhibitor of dopamine uptake (IC50 for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM).

Product Specifications

Molecular Weight

485.50

Formula

C28H32N2O.2HCl

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride

CAS Number

67469-75-4

PubChem ID

24744862

InChI Key

HJDXBLLTRMCYNC-JFXLULTRSA-N

SMILES

Cl[H].Cl[H].C(CN1CCN(C\C=C\C2=CC=CC=C2)CC1)OC(C1=CC=CC=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.27 50

Preparing Stock Solutions for GBR 12783 dihydrochloride

The following data is based on the product molecular weight 485.50

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.12 mL 20.60 mL 41.19 mL
2.5 mM 0.82 mL 4.12 mL 8.24 mL
5 mM 0.41 mL 2.06 mL 4.12 mL
25 mM 0.08 mL 0.41 mL 0.82 mL

Calculators

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Product Documents for GBR 12783 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GBR 12783 dihydrochloride

For research use only

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