Nomifensine

Tocris Bioscience, part of Bio-Techne | Catalog # 1992

Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
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Key Product Details

Description

Potent noradrenalin and dopamine uptake inhibitor. Antidepressant

View all Dopamine Transporter Inhibitors »

Product Description

Nomifensine is a potent inhibitor of noradrenaline and dopamine uptake (Ki values are 4.7, 26 and 4000 nM for inhibition of noradrenaline, dopamine and 5-HT uptake respectively, in rat brain). Increases central dopamine levels in rats following systemic administration. Displays antidepressant activity.

Product Specifications

Molecular Weight

354.40

Formula

C16H18N2.C4H4O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate

CAS Number

32795-47-4

PubChem ID

5358907

InChI Key

GEOCVSMCLVIOEV-BTJKTKAUSA-N

SMILES

NC1=CC=CC2=C1C[N+]([H])(C)CC2C3=CC=CC=C3.O=C(O)\C=C/C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.44 100

Preparing Stock Solutions for Nomifensine

The following data is based on the product molecular weight 354.40

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.82 mL 14.11 mL 28.22 mL
5 mM 0.56 mL 2.82 mL 5.64 mL
10 mM 0.28 mL 1.41 mL 2.82 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Nomifensine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Nomifensine

For research use only

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