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124 results for "PI 3-Kinase p110 gamma" in Products

PI 3-Kinase p110 gamma Products

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Chemical Name: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride
Purity: ≥99% (HPLC)
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, KO
Western Blot: PI 3-Kinase p110 gamma Antibody [NBP2-15071]
(4)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2A Monoclonal Clone #OTI2B1
Applications: IHC, WB
Western Blot: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]
(10)
Reactivity: Human
Details: Mouse IgG2a Kappa Monoclonal Clone #2G3
Applications: WB, ELISA, ICC/IF, Func
Immunocytochemistry/ Immunofluorescence: PI 3-Kinase p110 gamma Antibody (2G3) [H00005294-M02]
(3)

Potent and selective mTOR inhibitor

Chemical Name: 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)-one
Purity: ≥98% (HPLC)
Potent and selective mTOR inhibitor
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #304103
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