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228 results for "PARP" in Products

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PARP Products

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

PARP Antibody (194C1439) - Cleaved - BSA Free
Catalog #: NB100-56599
Citations (12)
Product Documents
Images (3)
Reactivity:
Human, Mouse, Rat (Negative)
Details:
Mouse IgG2b Kappa Monoclonal Clone #194C1439
Applications:
WB, Flow, ICC/IF
Western Blot: PARP Antibody (194C1439)CleavedBSA Free [NB100-56599]
(3)
Catalog #
Availability
Size / Price
Qty
NB100-56599
NB100-56599SS
Bulk Order

PARP Antibody (194C1439) - Cleaved - Azide and BSA Free
Catalog #: NBP2-27335
(1)
Citations (9)
Product Documents
Images (3)
Reactivity:
Human, Mouse, Rat (Negative)
Details:
Mouse IgG2b Kappa Monoclonal Clone #194C1439
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Western Blot: PARP Antibody (194C1439)CleavedAzide and BSA Free [NBP2-27335]
(3)
Catalog #
Availability
Size / Price
Qty
NBP2-27335
NBP2-27335SS
Bulk Order

PARP Antibody
Catalog #: AF-600-NA
(2)
Citations (10)
Product Documents
Images (5)
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, WB, ICC/IF, Simple Western, IP
Detection of Human PARP antibody by Western Blot.
(5)
Catalog #
Availability
Size / Price
Qty
AF-600-SP
AF-600-NA
Bulk Order

PARP Antibody - BSA Free
Catalog #: NBP2-13732
(1)
Citations (5)
Product Documents
Images (7)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF, Mycoplasma
Western Blot: PARP Antibody [NBP2-13732]
(7)
Catalog #
Availability
Size / Price
Qty
NBP2-13732-25ul
NBP2-13732
Bulk Order

Human PARP Antibody (839120)
Catalog #: MAB8095
(1)
Citations (3)
Product Documents
Images (4)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #839120
Applications:
KO, IHC, WB, Simple Western
Detection of Human PARP antibody by Western Blot.
(4)
Catalog #
Availability
Size / Price
Qty
MAB8095
MAB8095-SP
Bulk Order

PARP Antibody (CL2220) - BSA Free
Catalog #: NBP2-36747
Product Documents
Images (10)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL2220
Applications:
IHC, WB, ICC/IF, Mycoplasma
Western Blot: PARP Antibody (CL2220) [NBP2-36747]
(10)
Catalog #
Availability
Size / Price
Qty
NBP2-36747
NBP2-36747-25ul
Bulk Order

XAV 939
Catalog #: 3748
(1)
Citations (410)
Product Documents
Images (1)

Potent tankyrase inhibitor

GMP Version Available: TB3748-GMP
GMP
Alternate Names:
XAV939 Wnt Signaling Inhibitor
Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥98%
Potent tankyrase inhibitor
Catalog #
Availability
Size / Price
Qty
3748/10
3748/50
Bulk Order

PARP Antibody (CL2209) - BSA Free
Catalog #: NBP2-36748
Product Documents
Images (7)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL2209
Applications:
IHC, WB, Mycoplasma
Western Blot: PARP Antibody (CL2209) [NBP2-36748]
(7)
Catalog #
Availability
Size / Price
Qty
NBP2-36748
NBP2-36748-25ul
Bulk Order

PARP Antibody (2G8N7)
Catalog #: NBP3-15802
Product Documents
Images (14)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #2G8N7
Applications:
IHC, ELISA, ICC/IF
PARP Antibody (2G8N7)
(14)
Catalog #
Availability
Size / Price
Qty
NBP3-15802-100ul
NBP3-15802-20ul
Bulk Order

XAV 939GMP

Catalog #: TB3748-GMP
Product Documents
Images (1)

XAV 939 synthesized to cGMP guidelines

Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥99%
XAV 939 synthesized to cGMP guidelines
Catalog #
Availability
Size / Price
Qty
TB3748-GMP/10
Bulk Order

Nicotinamide
Catalog #: 4106
(1)
Citations (63)
Product Documents
Images (5)

PARP-1 inhibitor

Chemical Name:
Pyridine-3-carboxamide
Purity:
≥99%
iPSC-derived Human Intestinal Organoid
(5)
Catalog #
Availability
Size / Price
Qty
4106/50
Bulk Order

PARP Antibody
Catalog #: NBP3-09070
Product Documents
Images (4)
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB, Flow, ICC/IF
Western Blot: PARP Antibody [NBP3-09070]
(4)
Catalog #
Availability
Size / Price
Qty
NBP3-09070
Bulk Order

Biotin-NAD+
Catalog #: 6573
Citations (11)
Product Documents
Images (1)

Biotinylated-NAD+; substrate for ADP-ribosylation

Chemical Name:
β-Nicotinamide-N6-[2-[[6-[biotinyl]amino]hexyl]amino]-2-oxoethyl]adenine dinucleotide
Biotinylated-NAD+; substrate for ADP-ribosylation
Catalog #
Availability
Size / Price
Qty
6573/131U
Bulk Order

PARP Antibody (CL2209) - Azide and BSA Free
Catalog #: NBP3-44462
Product Documents
Images (7)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL2209
Applications:
IHC, WB
PARP Antibody (CL2209) - Azide and BSA Free Immunohistochemistry-Paraffin: PARP Antibody [NBP3-44462]
(7)
Catalog #
Availability
Size / Price
Qty
NBP3-44462
Bulk Order

EB 47
Catalog #: 4140
(1)
Citations (6)
Product Documents
Images (1)

Potent PARP-1 inhibitor

Chemical Name:
5'-Deoxy-5'-[4-[2-[(2,3-Dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine dihydrochloride
Purity:
≥98%
Potent PARP-1 inhibitor
Catalog #
Availability
Size / Price
Qty
4140/10
4140/50
Bulk Order

PARP Antibody (8C7) - BSA Free
Catalog #: NBP3-26439
Product Documents
Images (5)

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #8C7
Applications:
IHC, WB, ELISA, Flow, ICC/IF
PARP Antibody (8C7)
(5)
Catalog #
Availability
Size / Price
Qty
NBP3-26439-100ul
NBP3-26439-50ul
Bulk Order

PARP Antibody (CL2220) - Azide and BSA Free
Catalog #: NBP3-44461
Product Documents
Images (5)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #CL2220
Applications:
IHC, WB
PARP Antibody (CL2220) - Azide and BSA Free Immunohistochemistry-Paraffin: PARP Antibody [NBP3-44461]
(5)
Catalog #
Availability
Size / Price
Qty
NBP3-44461
Bulk Order

PARPi-FL
Catalog #: 6461
Citations (6)
Product Documents
Images (1)

Potent fluorescent PARP inhibitor; cell permeable

Alternate Names:
AZD2281-BDY FL,Olaparib-BDY FL
Chemical Name:
(T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron
Purity:
≥90%
Potent fluorescent PARP inhibitor; cell permeable
Catalog #
Availability
Size / Price
Qty
6461/1
Bulk Order

Olaparib
Catalog #: 7579
(1)
Citations (21)
Product Documents
Images (1)

Potent PARP inhibitor

Chemical Name:
4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone
Purity:
≥98%
Potent PARP inhibitor
Catalog #
Availability
Size / Price
Qty
7579/10
7579/50
Bulk Order

PARP Antibody (7C11) - BSA Free
Catalog #: NBP3-26438
Product Documents
Images (3)

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #7C11
Applications:
IHC, WB, ELISA
PARP Antibody (7C11)
(3)
Catalog #
Availability
Size / Price
Qty
NBP3-26438-100ul
NBP3-26438-50ul
Bulk Order

PJ 34 hydrochloride
Catalog #: 3255
Citations (3)
Product Documents
Images (1)

Potent PARP inhibitor

Chemical Name:
N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride
Purity:
≥98%
Potent PARP inhibitor
Catalog #
Availability
Size / Price
Qty
3255/10
3255/50
Bulk Order

AZD 2461
Catalog #: 6060
Citations (4)
Product Documents
Images (1)

Potent PARP inhibitor; orally bioavailable

Chemical Name:
4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone
Purity:
≥98%
Potent PARP inhibitor; orally bioavailable
Catalog #
Availability
Size / Price
Qty
6060/50
6060/10
Bulk Order

Rucaparib camsylate
Catalog #: 6230
Citations (2)
Product Documents
Images (1)

PARP inhibitor

Alternate Names:
CO-338
Chemical Name:
8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid
Purity:
≥98%
PARP inhibitor
Catalog #
Availability
Size / Price
Qty
6230/10
6230/50
Bulk Order

OUL 35
Catalog #: 6344
Citations (3)
Product Documents
Images (1)

Selective PARP-10 inhibitor

Chemical Name:
4,4'-Oxybis[benzamide]
Purity:
≥98%
Selective PARP-10 inhibitor
Catalog #
Availability
Size / Price
Qty
6344/25
6344/5
Bulk Order

OUL 35
Catalog #: 6344
Citations (3)
Product Documents
Images (1)

Selective PARP-10 inhibitor

Chemical Name:
4,4'-Oxybis[benzamide]
Purity:
≥98%
Selective PARP-10 inhibitor
Catalog #
Availability
Size / Price
Qty
6344/25
6344/5
Bulk Order
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