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p38 beta/MAPK11 Products

The p38 mitogen-activated protein kinases (p38 MAP kinases) are a family of four related Ser/Thr kinases responsive to pro-inflammatory cytokines and environmental stresses, including ionizing radiation, oxidative stress, and osmotic shock. Each family member, p38 alpha, p38 beta, p38 delta, and p38 gamma, is activated by dual Thr and Tyr phosphorylation within a Thr-Gly-Tyr motif residing in the kinase activation loop. For p38 beta, also known as p38-2, stress-activated protein kinase 2B (SAPK2B), and MAPK11, this dual phosphorylation occurs at Thr180/Tyr182.

13 results for "p38 beta/MAPK11" in Products

p38 beta/MAPK11 Products

The p38 mitogen-activated protein kinases (p38 MAP kinases) are a family of four related Ser/Thr kinases responsive to pro-inflammatory cytokines and environmental stresses, including ionizing radiation, oxidative stress, and osmotic shock. Each family member, p38 alpha, p38 beta, p38 delta, and p38 gamma, is activated by dual Thr and Tyr phosphorylation within a Thr-Gly-Tyr motif residing in the kinase activation loop. For p38 beta, also known as p38-2, stress-activated protein kinase 2B (SAPK2B), and MAPK11, this dual phosphorylation occurs at Thr180/Tyr182.

13 results for "p38 beta/MAPK11" in Products

ICC

Potent, selective inhibitor of p38 MAPK

Selective inhibitor of p38 MAPK

High affinity and selective p38 kinase inhibitor

Selective inhibitor of p38 MAPK; water-soluble

Selective inhibitor of p38α and p38β2

p38 MAPK inhibitor; anti-inflammatory

Potent and selective p38α/β inhibitor

Potent, selective p38α and p38β inhibitor

p38 MAPK inhibitor

Selective p38 MAPK inhibitor

Potent and selective p38α and p38β Degrader (PROTAC®); active in vivo

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