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11 results for "other-er-stress-upr-inhibitors&view=expanded" in Products

Selective inhibitor of eIF2α dephosphorylation

Chemical Name:
3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide
Purity:
≥98%
Selective inhibitor of eIF2α dephosphorylation

Selective inhibitor of ATF6α; sensitizes cells to ER stress

Chemical Name:
N-[1-[[2,4-bis(Trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide
Purity:
≥98%
Selective inhibitor of ATF6α; sensitizes cells to ER stress

Potent inhibitor of ER-associated protein degradation and translocation

Chemical Name:
3-(4-Chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5,5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide
Purity:
≥98%
Potent inhibitor of ER-associated protein degradation and translocation

Potent and selective p97 ATPase (VCP) allosteric inhibitor

Chemical Name:
3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine
Purity:
≥98%
Potent and selective p97 ATPase (VCP) allosteric inhibitor

Integrated stress response (ISR) inhibitor

Chemical Name:
N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]
Purity:
≥98%
Integrated stress response (ISR) inhibitor

Dimeric Smac mimetic; potent IAP inhibitor

Chemical Name:
3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolinamide
Purity:
≥97%
Dimeric Smac mimetic; potent IAP inhibitor

ATP-competitive inhibitor of p97 ATPase

Chemical Name:
2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine
Purity:
≥98%
ATP-competitive inhibitor of p97 ATPase

Potent and selective ASK1 inhibitor; orally bioavailable

Chemical Name:
4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride
Purity:
≥98%
Potent and selective ASK1 inhibitor; orally bioavailable

ERα antagonist; also activates unfolded protein response; active in vivo

Chemical Name:
1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one
Purity:
≥98%
ERα antagonist; also activates unfolded protein response; active in vivo

SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Chemical Name:
N-(4-Butyl-2-methylphenyl)acetamide
Purity:
≥98%
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
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