Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Integrated stress response (ISR) inhibitor|
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Citations for trans-ISRIB (3)
Citations are publications that use Bio-Techne products. Selected citations for trans-ISRIB include:
Tristan et al.
Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells.
Stem Cell Rep..
Chen et al.
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells.
GADD34 function in protein trafficking promotes adaptation to hyperosmotic stress in human corneal cells.
There are no citations that match your criteria.
Customer Reviews for trans-ISRIB (2)
Species: HumanAssay Type: In VitroCell Line/Tissue: HEK293Used trans-ISRIB to inhibit the integrated stress response (ISR) in HEK293 cells. Induced the ISR and added ISRIB (100 and 500nM) overnight. Evaluated p-eif2a (unchanged) and cleaved caspase 3 (increased in a dose-dependent manner with ISRIB.
Species: RatAssay Type: In VitroCell Line/Tissue: cortical neuronsToxicity assay. 500 nM concentration was used. Highly effective Integrated stress response (ISR) inhibitor. Works very well.
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