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mGluR8 Products

The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.

18 results for "mGluR8" in Products

mGluR8 Products

The Group III metabotropic glutamate receptors include mGluR4, 6, 7 and 8. These 7-transmembrane glycoproteins are negatively coupled to adenylate cyclase and expressed presynaptically throughout the brain. MGluR8 shows pronounced expression in the dentate gyrus and CA3 regions of the hippocampus, and is thought to play a role in memory formation.

18 results for "mGluR8" in Products

WB, IHC
Catalog #: 9534-UR
Catalog #: RDC1002
IHC
ICC/IF, IHC
ELISA, Flow, WB
ELISA, WB

Selective group III mGlu agonist

Potent and highly selective group II mGlu agonist

Potent group III mGlu antagonist

Potent and selective mGlu8a agonist

Positive allosteric modulator of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant

Positive allosteric modulator of group I mGlu receptors

Selective positive allosteric modulator of group III mGlu receptors

Active metabolite of oxcarbazepine (Cat. No. 3864)

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