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Group III mGluR Antagonists Small Molecule

Key Product Details

Description: Potent group III mGlu antagonist
Chemical Name: (RS)-α-Cyclopropyl-4-phosphonophenylglycine
Purity: ≥98% (HPLC)
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Citations (21)

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  • Used in inhibitor cocktail
    Name: Anonymous | 3rd Dec 2019
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Retinal rod bipolar cells
    Retinal dissections were performed in HEPES-buffered extracellular solution containing glutamate inhibitor cocktail - 600 umol/L
    Used in inhibitor cocktail Serum 0972
  • Use of CPPG as a blocker of mGluRs group III
    Name: Anonymous | 17th Sep 2019
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Cerebellum
    CPPG (5 microM) was used for pharmacological isolation of GABA-A receptor activity in nucleated membrane patches. Being added to perfusion solution, CPPG blocked contaminating receptor activity in a recorded response, thus revealing clear GABA-ergic single-channel openings. Figure: single-channel openings of GABA-A receptors in a membrane patch after application of CPPG.
    Compound should be sonicated when dissolving.
    Use of CPPG as a blocker of mGluRs group III Serum 0972

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