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Lysine Methyltransferase Inhibitors Products
25 results for "Lysine Methyltransferase Inhibitors" in Products
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Lysine Methyltransferase Inhibitors Products
25 results for "Lysine Methyltransferase Inhibitors" in Products
SETD8 inhibitor; also CDK4 inhibitor
| Chemical Name : | 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione |
| Purity : | ≥98% (HPLC) |
EZH2 histone methyltransferase inhibitor
| Alternate Names : | DZNep, NSC 617989 |
| Chemical Name : | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity : | ≥98% (HPLC) |
SUV39H1 inhibitor
| Chemical Name : | (3S,3'S,5aR,5aR,10bR,10'bR,11aS,11'aS)-2,2',3,3',5a,5'a,6,6'-octahydro-3,3'-bis(hydroxymethyl)-2,2'-dimethyl-[10b,10'b(11H,11'H)-bi3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone |
| Purity : | ≥95% (HPLC) |
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
| Chemical Name : | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity : | ≥98% |
Very high affinity and selective EZH2 inhibitor
| Chemical Name : | N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent G9a and GLP inhibitor
| Chemical Name : | 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine |
| Purity : | ≥98% (HPLC) |
Potent and selective SAM-competitive EZH2 inhibitor
| Chemical Name : | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent and selective SETD7 inhibitor
| Chemical Name : | 8-Fluoro-1,2,3,4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride |
| Purity : | ≥97% (HPLC) |
Highly potent and selective DOT1L inhibitor; cell permeable
| Chemical Name : | 1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl](isopropyl)amino]propyl]-3-[4-(2,2-dimethylethyl)phenyl]urea |
| Purity : | ≥99% (HPLC) |
Potent and selective G9a and GLP inhibitor
| Chemical Name : | 2-(4,4-Difluoro-1-piperidinyl)-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
| Purity : | ≥99% (HPLC) |
Selective G9a and GLP inhibitor
| Chemical Name : | 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
| Purity : | ≥98% (HPLC) |
GLP and G9a inhibitor
| Chemical Name : | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent and selective EZH2/EZH1 inhibitor
| Chemical Name : | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide |
| Purity : | ≥99% (HPLC) |
Antagonizes PWWP1 interaction with nucleosomal H3K36me2, alters NSD2 nucleolar localization
| Chemical Name : | N-Cyclopropyl-3,4-dihydro-3-oxo-N-[[4-[(4-pyrimidinylamino)carbonyl]phenyl]methyl]-2H-1,4-benzoxazine-7-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent and selective G9a/GLP inhibitor
| Chemical Name : | 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine |
| Purity : | ≥98% (HPLC) |
Potent and selective SAM-competitive EZH2 inhibitor
| Chemical Name : | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent and selective SUV420H1/H2 inhibitor
| Chemical Name : | 6,7-Dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine |
| Purity : | ≥98% (HPLC) |
Potent and selective SMYD3 inhibitor
| Chemical Name : | (2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide |
| Purity : | ≥98% (HPLC) |
Highly potent DOT1L inhibitor
| Chemical Name : | 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Purity : | ≥98% (HPLC) |
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
| Chemical Name : | 8-Fluoro-1,2,3,4-tetrahydro-N-[(1S)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride |
| Purity : | ≥97% (HPLC) |
Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain
| Chemical Name : | (4-(5-(7-Fluoroquinolin-4-yl)-1-methyl-1H-imidazol-4-yl)-3,5-dimethylphenyl)methanamine trihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent PRDM9 inhibitor
| Chemical Name : | 3-(3,5-Dimethoxyphenyl)-5-(1-methyl-9-(2-methylpyridin-4-yl)-1,4,9-triazaspiro[5.5]undecan-4-yl)-1,2,4-oxadiazole |
| Purity : | ≥98% (HPLC) |
Highly potent and SAM-competitive EZH2 inhibitor
| Chemical Name : | 5,8-Dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1(2H)-isoquinolinone acetate |
| Purity : | ≥97% (HPLC) |
Biotinylated UNC 1999 (Cat.No. 4904)
| Chemical Name : | 1-Isopropyl-N-[(6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl]-6-[6-[4-[41-oxo-45-[(3aS,4aS,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-40-azapentatetracontan-1oyl]piperazin-1-yl]pyridin-3-yl]-1H-indazole-4-carboxamide |
| Purity : | ≥95% (HPLC) |
Potent and selective EED inhibitor
| Chemical Name : | N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine |
| Purity : | ≥98% (HPLC) |
