Lysine Methyltransferase Inhibitors Products
25 results for "Lysine Methyltransferase Inhibitors" in Products
Search
Product Action
Conjugates
Low Endotoxin
Sample Size
Citations
Lysine Methyltransferase Inhibitors Products
25 results for "Lysine Methyltransferase Inhibitors" in Products
SETD8 inhibitor; also CDK4 inhibitor
Chemical Name : | 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione |
Purity : | ≥98% (HPLC) |
EZH2 histone methyltransferase inhibitor
Alternate Names : | DZNep, NSC 617989 |
Chemical Name : | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
Purity : | ≥98% (HPLC) |
SUV39H1 inhibitor
Chemical Name : | (3S,3'S,5aR,5aR,10bR,10'bR,11aS,11'aS)-2,2',3,3',5a,5'a,6,6'-octahydro-3,3'-bis(hydroxymethyl)-2,2'-dimethyl-[10b,10'b(11H,11'H)-bi3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone |
Purity : | ≥95% (HPLC) |
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
Chemical Name : | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
Purity : | ≥98% |
Very high affinity and selective EZH2 inhibitor
Chemical Name : | N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide |
Purity : | ≥98% (HPLC) |
Potent G9a and GLP inhibitor
Chemical Name : | 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine |
Purity : | ≥98% (HPLC) |
Potent and selective SAM-competitive EZH2 inhibitor
Chemical Name : | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide |
Purity : | ≥98% (HPLC) |
Potent and selective SETD7 inhibitor
Chemical Name : | 8-Fluoro-1,2,3,4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride |
Purity : | ≥97% (HPLC) |
Highly potent and selective DOT1L inhibitor; cell permeable
Chemical Name : | 1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl](isopropyl)amino]propyl]-3-[4-(2,2-dimethylethyl)phenyl]urea |
Purity : | ≥99% (HPLC) |
Potent and selective G9a and GLP inhibitor
Chemical Name : | 2-(4,4-Difluoro-1-piperidinyl)-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
Purity : | ≥99% (HPLC) |
Selective G9a and GLP inhibitor
Chemical Name : | 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
Purity : | ≥98% (HPLC) |
GLP and G9a inhibitor
Chemical Name : | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
Purity : | ≥98% (HPLC) |
Potent and selective EZH2/EZH1 inhibitor
Chemical Name : | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide |
Purity : | ≥99% (HPLC) |
Antagonizes PWWP1 interaction with nucleosomal H3K36me2, alters NSD2 nucleolar localization
Chemical Name : | N-Cyclopropyl-3,4-dihydro-3-oxo-N-[[4-[(4-pyrimidinylamino)carbonyl]phenyl]methyl]-2H-1,4-benzoxazine-7-carboxamide |
Purity : | ≥98% (HPLC) |
Potent and selective G9a/GLP inhibitor
Chemical Name : | 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine |
Purity : | ≥98% (HPLC) |
Potent and selective SAM-competitive EZH2 inhibitor
Chemical Name : | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide |
Purity : | ≥98% (HPLC) |
Potent and selective SUV420H1/H2 inhibitor
Chemical Name : | 6,7-Dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine |
Purity : | ≥98% (HPLC) |
Potent and selective SMYD3 inhibitor
Chemical Name : | (2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide |
Purity : | ≥98% (HPLC) |
Highly potent DOT1L inhibitor
Chemical Name : | 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Purity : | ≥98% (HPLC) |
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
Chemical Name : | 8-Fluoro-1,2,3,4-tetrahydro-N-[(1S)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride |
Purity : | ≥97% (HPLC) |
Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain
Chemical Name : | (4-(5-(7-Fluoroquinolin-4-yl)-1-methyl-1H-imidazol-4-yl)-3,5-dimethylphenyl)methanamine trihydrochloride |
Purity : | ≥98% (HPLC) |
Potent PRDM9 inhibitor
Chemical Name : | 3-(3,5-Dimethoxyphenyl)-5-(1-methyl-9-(2-methylpyridin-4-yl)-1,4,9-triazaspiro[5.5]undecan-4-yl)-1,2,4-oxadiazole |
Purity : | ≥98% (HPLC) |
Highly potent and SAM-competitive EZH2 inhibitor
Chemical Name : | 5,8-Dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1(2H)-isoquinolinone acetate |
Purity : | ≥97% (HPLC) |
Biotinylated UNC 1999 (Cat.No. 4904)
Chemical Name : | 1-Isopropyl-N-[(6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl]-6-[6-[4-[41-oxo-45-[(3aS,4aS,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-40-azapentatetracontan-1oyl]piperazin-1-yl]pyridin-3-yl]-1H-indazole-4-carboxamide |
Purity : | ≥95% (HPLC) |
Potent and selective EED inhibitor
Chemical Name : | N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine |
Purity : | ≥98% (HPLC) |