Key Product Details
Description: | Potent and selective SETD7 inhibitor |
Chemical Name: | 8-Fluoro-1,2,3,4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride |
Purity: | ≥97% (HPLC) |
Molecular Weight: | 535.98 |
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Citations for (R)-PFI 2 hydrochloride (3)
Citations are publications that use Bio-Techne products. Selected citations for (R)-PFI 2 hydrochloride include:
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Judson et al.
(2018)
Inhibition of methyltransferase Setd7 allows in vitro expansion of myogenic stem cells with improved therapetic potential.
Cell Stem Cell.
22:177
PMID: 29395054 -
Liu et al.
(2015)
Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation.
J Neuroinflammation.
43:5081
PMID: 25897119 -
Barsyte-Lovejoy et al.
(2014)
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
Proc Natl Acad Sci U S A.
111:12853
PMID: 25136132
There are no citations that match your criteria.