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LAIR1 Products
LAIR1 (leukocyte-associated Ig-like receptor-1; CD305) is a transmembrane collagen-binding protein that is expressed in a differentiation- and activation-dependent manner on T, B, NK and dendritic cells, monocytes, CD34+ hematopoietic progenitors, most thymocytes, and select granulocyte populations. LAIR1 mediated adhesion to collagens in the extracellular matrix inhibits B and T cell receptor-mediated activation, NK and T cell-mediated cytotoxicity, and basophil degranulation. LAIR1 is reduced or absent on human B cell chronic lymphocytic leukemia (CLL) and some B and dendritic cells in systemic lupus erythematosus (SLE). A soluble form of LAIR1 found in plasma and urine also binds collagen.
25 results for "LAIR1" in Products
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LAIR1 Products
LAIR1 (leukocyte-associated Ig-like receptor-1; CD305) is a transmembrane collagen-binding protein that is expressed in a differentiation- and activation-dependent manner on T, B, NK and dendritic cells, monocytes, CD34+ hematopoietic progenitors, most thymocytes, and select granulocyte populations. LAIR1 mediated adhesion to collagens in the extracellular matrix inhibits B and T cell receptor-mediated activation, NK and T cell-mediated cytotoxicity, and basophil degranulation. LAIR1 is reduced or absent on human B cell chronic lymphocytic leukemia (CLL) and some B and dendritic cells in systemic lupus erythematosus (SLE). A soluble form of LAIR1 found in plasma and urine also binds collagen.
25 results for "LAIR1" in Products
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2459C |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Assay Range : | 39.1 - 2,500 pg/mL |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | Q6GTX8 |
| Applications : | Bioactivity |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2459B |
| Applications : | Block/Neutralize |
Biotinylated
| Source : | HEK293 |
| Accession # : | NP_002278.2 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | XP_015297320.1 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Source : | NS0 |
| Accession # : | Q8BG84 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | NP_002278 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Source : | NS0 |
| Accession # : | Q8BG84 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #342219 |
| Applications : | Flow Cytometry |
