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Inositol Lipid Inhibitors: Small Molecules and Peptides

Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells. These include inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.

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6 results for "Inositol Lipid Inhibitors Small Molecules and Peptides" in Products

6 results for "Inositol Lipid Inhibitors Small Molecules and Peptides" in Products

Inositol Lipid Inhibitors: Small Molecules and Peptides

Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells. These include inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.

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Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Chemical Name: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride
Purity: ≥99% (HPLC)
Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1

Alternate Names: SL-2052
Chemical Name: (1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6,9-trione
Purity: ≥98% (HPLC)
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1

Inositol monophosphatase inhibitor

Chemical Name: [1-(4-Hydroxyphenoxy)ethylidene]bisphosphonic acid
Inositol monophosphatase inhibitor

Non-selective PI 3-kinase inhibitor

Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
Purity: ≥98% (HPLC)
Non-selective PI 3-kinase inhibitor

Class III PI 3-kinase inhibitor; also inhibits autophagy

Alternate Names: 3-MA
Chemical Name: 3-Methyl-3H-purin-6-amine
Purity: ≥98% (HPLC)
Class III PI 3-kinase inhibitor; also inhibits autophagy

Potent and selective PI 3-Kβ inhibitor

Chemical Name: (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid
Purity: ≥98%
Potent and selective PI 3-Kβ inhibitor
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