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IL-27 Products

IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.

33 results for "IL-27" in Products

IL-27 Products

IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.

33 results for "IL-27" in Products

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

His-tag

CyTOF-ready, ICFlow
Catalog #: MAB18343
IP
Catalog #: RDC2737
BA
CyTOF-ready, ICFlow
Catalog #: IC25261N
ICFlow
ICFlow
Catalog #: IC18342R
ICFlow
Catalog #: IC18342U
ICFlow
Catalog #: RDC2335
BA

Biotinylated

ICFlow
Catalog #: IC25261V
ICFlow
Catalog #: IC25261G
ICFlow
Catalog #: IC25261R
ICFlow
Catalog #: IC25261U
ICFlow
Catalog #: IC25261S
ICFlow
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