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IL-27 Products
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
33 results for "IL-27" in Products
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IL-27 Products
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
33 results for "IL-27" in Products
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
BA
| Source : | NS0 |
| Accession # : | O35228 (EBI3) & Q8K3I6 (p28) |
| Applications : | Bioactivity |
BA
His-tag
| Source : | NS0 |
| Accession # : | Q14213.2 (EBI3) & AAM34498 (p28) |
| Applications : | Bioactivity |
CyTOF-ready, ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | CyTOF-ready, Flow Cytometry |
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Catalog #:
MAB18343
IP
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #355028 |
| Applications : | Immunoprecipitation |
ELISA
| Assay Range : | 156 - 10,000 pg/mL |
| Applications : | ELISA |
Catalog #:
10307-IL
BA
| Source : | CHO |
| Accession # : | XP_005587614.1 (EBI-3) & XP_028697194.1 (IL-27a) |
| Applications : | Bioactivity |
WB, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, ELISA Capture, Western Blot |
Catalog #:
MAB18342
CyTOF-ready, ICFlow
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #355025 |
| Applications : | CyTOF-ready, Flow Cytometry |
Catalog #:
IC25261N
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261P
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC18342R
ICFlow
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #355025 |
| Applications : | Flow Cytometry |
Catalog #:
IC18342U
ICFlow
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #355025 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261A
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261V
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261G
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261R
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261U
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
Catalog #:
IC25261S
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #307426 |
| Applications : | Flow Cytometry |
