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IL-27: Proteins and Enzymes
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
4 results for "IL-27 Proteins and Enzymes" in Products
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IL-27: Proteins and Enzymes
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
4 results for "IL-27 Proteins and Enzymes" in Products
BA
| Source : | NS0 |
| Accession # : | O35228 (EBI3) & Q8K3I6 (p28) |
| Applications : | Bioactivity |
BA
His-tag
| Source : | NS0 |
| Accession # : | Q14213.2 (EBI3) & AAM34498 (p28) |
| Applications : | Bioactivity |
Catalog #:
10307-IL
BA
| Source : | CHO |
| Accession # : | XP_005587614.1 (EBI-3) & XP_028697194.1 (IL-27a) |
| Applications : | Bioactivity |
