Human IL-27 Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human |
Immunogen: |
Mouse myeloma cell line NS0-derived recombinant human IL‑27 (R&D Systems, Catalog # 2526-IL) Arg21-Lys229 (IL-27 EBI-3 subunit), Phe29-Pro243 (IL-27 p28 subunit) Accession # Q14213 (EBI-3 subunit), AAM34498 (p28 subunit) |
Applications: | Block/Neutralize, ELISA Capture, Western Blot |
Label: | Unconjugated |
Source: | Polyclonal Goat IgG |
Specificity: |
Detects human IL-27 in ELISAs and Western blots. |
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Citations for Human IL-27 Antibody (11)
Citations are publications that use Bio-Techne products. Selected citations for Human IL-27 Antibody include:
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Species: Human
Sample Types: Whole Cells
Applications: NeutralizationXY Zhang et al. (2022), IL-27 promotes decidualization via the STAT3-ESR/PGR regulatory axis Journal of reproductive immunology, 151(0):103623.
PMID: 35430461 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationI Gregersen et al. (2017), Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation PLoS ONE, 12(11):e0188387.
PMID: 29176764 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationA Garg et al. (2017), Human Immunodeficiency Virus Type-1 Myeloid Derived Suppressor Cells Inhibit Cytomegalovirus Inflammation through Interleukin-27 and B7-H4 Sci Rep, 7(0):44485.
PMID: 28338007 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development (Capture)N Gajanayaka et al. (2017), HIV and HIV-Tat inhibit LPS-induced IL-27 production in human macrophages by distinct intracellular signaling pathways J. Leukoc. Biol., 0(0).
PMID: 28698313 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationJK Sprokholt et al. (2017), RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production PLoS Pathog., 13(11):e1006738.
PMID: 29186193 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationG Tan et al. (2017), Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication Cell. Mol. Immunol, 0(0).
PMID: 28194021 -
Species: Human
Sample Types: Whole Cells
Applications: IHCXie M et al. (2015), IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling. J Allergy Clin Immunol, 135(2):386-94.
PMID: 25312760 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationFitzgerald D et al. (2013), Independent and interdependent immunoregulatory effects of IL-27, IFN-beta, and IL-10 in the suppression of human Th17 cells and murine experimental autoimmune encephalomyelitis. J Immunol, 190(7):3225-34.
PMID: 23455508 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationRamgolam VS et al. (2011), B cells as a therapeutic target for IFN-beta in relapsing-remitting multiple sclerosis. J. Immunol., 186(0):4518.
PMID: 21368231 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA DevelopmentKalliolias GD et al. (2010), Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27. J. Immunol., 185(11):7047-56.
PMID: 20971923 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationGringhuis S et al. (0), Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production. Nat Commu5(0):5074.
PMID: 25278262
There are no citations that match your criteria.
Customer Reviews for Human IL-27 Antibody (1)
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Application: ELISASample Tested: Serum and PlasmaSpecies: HumanVerified Customer | Posted 11/27/2017AF2526 was used as the solid phase antibody, BAF2526 was used as the detection antibody. 2526-IL was used as the immunoassay standard. Sensitivity of the assay was around 100 pg/ml.
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