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ICAM-1/CD54 Products
ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
61 results for "ICAM-1/CD54" in Products
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ICAM-1/CD54 Products
ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
61 results for "ICAM-1/CD54" in Products
Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Source : | NS0 |
| Accession # : | Q3U8M7 |
| Applications : | Bioactivity |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 29 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Simple Plex Human ICAM-1/CD54 assay kit for use on Ella instrument. Contains cartridge, sample diluent 000303, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-I1 (11C81) |
| Applications : | Block/Neutralize, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Simple Western, Western Blot |
Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
| Source : | NS0 |
| Accession # : | CAA30051 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | CAA30051 |
| Applications : | Bioactivity |
| Sensitivity : | 0.254 ng/mL |
| Assay Range : | 1.56 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
| Sensitivity : | 0.053 ng/mL |
| Assay Range : | 0.625 - 40 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
| Sensitivity : | 0.057 ng/mL |
| Assay Range : | 0.31 - 20 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
