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ICAM-1/CD54: Antibodies

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1  (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

24 results for "ICAM-1/CD54 Primary Antibodies" in Products

ICAM-1/CD54: Antibodies

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1  (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

24 results for "ICAM-1/CD54 Primary Antibodies" in Products

WB, Simple Western, Flow, IP, AdBlk, ICC
WB, IHC, AdBlk
WB
WB
WB
WB, AdBlk, ICC, KO
WB, IHC, AdBlk
WB
Catalog #: MAB5832
WB, IHC, ICC, KO
Catalog #: FAB5831G
Flow
Catalog #: FAB5831T
Flow
Catalog #: FAB5831U
Flow
Catalog #: MAB5831
WB, Flow, CyTOF-ready
Catalog #: FAB5831R
Flow
Catalog #: FAB5831N
Flow
Catalog #: FAB5831V
Flow
Catalog #: FAB5831S
Flow
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