GRIN3A/NMDAR3A: Small Molecules and Peptides
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Products:
7 results for "GRIN3A/NMDAR3A Small Molecules and Peptides" in Products
7 results for "GRIN3A/NMDAR3A Small Molecules and Peptides" in Products
GRIN3A/NMDAR3A: Small Molecules and Peptides
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Products:
Non-competitive NMDA antagonist; acts at ion channel site
| Alternate Names: | Dizocilpine |
| Chemical Name: | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
| Purity: | ≥98% (HPLC) |
GluN2B-selective NMDA antagonist
| Chemical Name: | (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate |
| Purity: | ≥98% (HPLC) |
Broad spectrum glutamatergic antagonist
| Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
NMDA antagonist; acts at glycine site
| Chemical Name: | 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone |
| Purity: | ≥98% (HPLC) |
Highly potent NMDA antagonist
| Chemical Name: | trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline |
| Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist; acts at the glycine site
| Alternate Names: | GV 150526A |
| Chemical Name: | 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt |
| Purity: | ≥98% (HPLC) |
Potent and noncompetitive NMDA antagonist
| Alternate Names: | CNS 1102 |
| Chemical Name: | N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride |
| Purity: | ≥98% (HPLC) |
