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8 results for "GABA-B Receptor Antagonists" in Products

GABA-B Receptor Antagonists Products

GABAB receptors are GPCRs composed of seven transmembrane domains and a large extracellular N-terminal, and are responsible for mediating the inhibitory effects of GABA, alongside ionotropic GABAA and GABAA receptors. They are composed of 850 - 960 amino acids, and are most similar in structure to metabotropic glutamate receptors (mGluRs).

These receptors are heterodimers of GABAB1 and GABAB2 subunits. The GABAB1 subunit hosts the binding site for GABA and other ligands, while the GABAB2...

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Potent and selective GABAB antagonist

Chemical Name: (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride
Purity: ≥98% (HPLC)
Potent and selective GABAB antagonist

Selective and competitive GABAB antagonist; orally bioavailable

Chemical Name: (2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid
Purity: ≥98%
Selective and competitive GABAB antagonist; orally bioavailable

GABAB antagonist; displays activity at presynaptic receptors

Chemical Name: (3-Aminopropyl)ethylphosphinic acid hydrochloride
Purity: ≥98% (HPLC)
GABAB antagonist; displays activity at presynaptic receptors

Selective GABAB antagonist

Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid
Purity: ≥98% (HPLC)
Selective GABAB antagonist

Potent and selective GABAB antagonist

Chemical Name: [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid
Purity: ≥96% (HPLC)
Potent and selective GABAB antagonist

Selective GABAB antagonist; brain penetrant

Chemical Name: (3-Aminopropyl)(diethoxymethyl)phosphinic acid
Selective GABAB antagonist; brain penetrant

Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)

Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic acid
Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)

Potent and selective GABAB antagonist

Chemical Name: 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid
Purity: ≥98% (HPLC)
Potent and selective GABAB antagonist
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