Selective and competitive GABAB antagonist; orally bioavailable
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Key Product Details
Description: | Selective and competitive GABAB antagonist; orally bioavailable |
Chemical Name: | (2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid |
Purity: | ≥98% |
Molecular Weight: | 173.21 |
Citations for SCH 50911 (10)
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Citations are publications that use Bio-Techne products. Selected citations for SCH 50911 include:
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Kreye et al.
(2016)
Human cerebrospinal fluid monoclonal N-MthD.-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Brain.
139:2641
PMID: 27543972 -
Yu et al.
(2016)
Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy.
Neurobiol Dis.
89:23
PMID: 26804027 -
Jaiswal et al.
(2015)
Reduction in focal ictal activity following transplantation of MGE interneurons requires expression of the GABAA receptor α4 subunit.
J Psychopharmacol.
9:127
PMID: 25914623 -
Ding et al.
(2015)
The reinforcing effects of ethanol within the nucleus accumbens shell involve activation of local GABA and serotonin receptors.
Br J Pharmacol.
29:725
PMID: 25922425 -
Kitagawa et al.
(2009)
Prediction and validation of a mechanism to control the threshold for inhibitory synaptic plasticity.
Mol Syst Biol.
5:280
PMID: 19536203 -
Fritsch et al.
(2009)
Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis.
Neuroscience.
163:415
PMID: 19540312 -
Gryder et al.
(2005)
Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala.
Toxins (Basel).
94:1728
PMID: 16045445 -
Margeta-Mitrovic et al.
(2001)
Ligand-induced signal transduction within heterodimeric GABA(B) receptor.
Front Cell Neurosci.
98:14643
PMID: 11724957 -
Wood et al.
(2000)
The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.
J Neurochem.
131:1050
PMID: 11082110 -
Vogt and Nicoll
(1999)
Glutamate and gamma-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus.
Proc Natl Acad Sci U S A.
96:1118
PMID: 9927703
There are no citations that match your criteria.