CGP 35348

Tocris Bioscience, part of Bio-Techne | Catalog # 1245

Selective GABAB antagonist; brain penetrant
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Key Product Details

Description

Selective GABAB antagonist; brain penetrant

View all GABA-B Receptor Antagonists »

Product Description

CGP 35348 is a selective, brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.

Licensing Information

Sold with the permission of Novartis Pharma AG

Product Specifications

Molecular Weight

225.22

Formula

C8H20NO4P

Storage

Store at RT

Chemical Name

(3-Aminopropyl)(diethoxymethyl)phosphinic acid

CAS Number

123690-79-9

PubChem ID

107699

InChI Key

QIIVUOWTHWIXFO-UHFFFAOYSA-N

SMILES

NCCCP(C(OCC)OCC)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for CGP 35348

The following data is based on the product molecular weight 225.22

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.44 mL 22.20 mL 44.40 mL
5 mM 0.89 mL 4.44 mL 8.88 mL
10 mM 0.44 mL 2.22 mL 4.44 mL
50 mM 0.09 mL 0.44 mL 0.89 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for CGP 35348

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CGP 35348

For research use only

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