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Endoglin/CD105 Products

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

47 results for "Endoglin/CD105" in Products

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Endoglin/CD105 Products

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

47 results for "Endoglin/CD105" in Products

Simple Plex Human Endoglin/CD105 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Catalog #: 898084

Control for use with Human Endoglin/CD105 Simple Plex Cartridge Kit

WB, Simple Western, Flow, IHC, CyTOF-ready, ICC, KO
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
WB, Flow, IHC, CyTOF-ready, ICC
WB, IHC, ICC
Flow, CyTOF-ready
WB, Flow, IHC
WB, IHC, IP, ICC
Catalog #: FAB10971U
Flow
WB
BA
Catalog #: FAB1320R
Flow
Catalog #: MAB13201
WB

A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!

BA
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