
Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
48 results for "Endoglin/CD105" in Products
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Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
48 results for "Endoglin/CD105" in Products
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Sensitivity : | 0.03 ng/mL |
Assay Range : | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Selective estrogen receptor modulator (SERM)
Alternate Names : | LY 139481, Keoxifene |
Chemical Name : | [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride |
Purity : | ≥98% (HPLC) |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #166709 |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Knockout Validated, Simple Western, Western Blot |
A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!
Simple Plex Cartridge Kit for quantitation of Endoglin. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Assay Range : | 125 - 8,000 pg/mL |
Applications : | ELISA |
Sensitivity : | 13.6 pg/mL |
Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #209701 |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #166707 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #166707 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #166713 |
Applications : | ELISA Capture |
Assay Range : | 62.5 - 4,000 pg/mL |
Applications : | ELISA |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Flow Cytometry, Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
Source : | CHO |
Accession # : | P37176 |
Applications : | Bioactivity |