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Endoglin/CD105 Products

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

48 results for "Endoglin/CD105" in Products

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Endoglin/CD105 Products

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

48 results for "Endoglin/CD105" in Products

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

WB, Simple Western, Flow, IHC, CyTOF-ready, ICC

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Selective estrogen receptor modulator (SERM)

WB
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC, KO
BA

A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!

Simple Plex Cartridge Kit for quantitation of Endoglin. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

WB, Flow, IHC, CyTOF-ready, ICC
Catalog #: FAB10971R
Flow
WB, IHC, ICC
WB, Flow, IHC
WB, IHC, IP, ICC
Catalog #: 5605-EN
BA
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