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Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
47 results for "Endoglin/CD105" in Products
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Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
47 results for "Endoglin/CD105" in Products
Simple Plex Human Endoglin/CD105 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Sensitivity : | 0.03 ng/mL |
| Assay Range : | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Knockout Validated, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | Flow Cytometry |
| Sensitivity : | 13.6 pg/mL |
| Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #209701 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | Flow Cytometry |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Flow Cytometry, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166713 |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166709 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #209701 |
| Applications : | Flow Cytometry |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | Q8K100 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #209701 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #209721 |
| Applications : | ELISA Capture, Western Blot |
A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!
| Source : | CHO |
| Accession # : | P17813 |
| Applications : | Bioactivity |
