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Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
48 results for "Endoglin/CD105" in Products
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Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
48 results for "Endoglin/CD105" in Products
Catalog #:
ARY012
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ELISA
| Sensitivity : | 0.03 ng/mL |
| Assay Range : | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Selective estrogen receptor modulator (SERM)
| Alternate Names : | LY 139481, Keoxifene |
| Chemical Name : | [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride |
| Purity : | ≥98% (HPLC) |
Catalog #:
MAB1097
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166709 |
| Applications : | Western Blot |
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC, KO
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Knockout Validated, Simple Western, Western Blot |
Catalog #:
1097-EN
BA
A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!
Catalog #:
SPCKB-PS-000371
Simple Plex Cartridge Kit for quantitation of Endoglin. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
ELISA
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
ELISA
| Sensitivity : | 13.6 pg/mL |
| Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
WB, Flow, IHC, CyTOF-ready, ICC
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #209701 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | Flow Cytometry |
Catalog #:
FAB10971R
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166707 |
| Applications : | Flow Cytometry |
Catalog #:
MAB10972
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #166713 |
| Applications : | ELISA Capture |
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
WB, IHC, ICC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
WB, Flow, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Flow Cytometry, Immunohistochemistry, Western Blot |
WB, IHC, IP, ICC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Source : | CHO |
| Accession # : | P37176 |
| Applications : | Bioactivity |
