Human Endoglin/CD105 Quantikine ELISA Kit
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Assay Length: | 4.5 hours |
Sample Type & Volume Required Per Well: | Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL) |
Sample Types: | Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma |
Sensitivity: | 0.03 ng/mL |
Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Human Endoglin/CD105 Quantikine ELISA Kit Summary: |
The Quantikine Human Endoglin Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Endoglin in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Endoglin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Endoglin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring Endoglin. |
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Citations for Human Endoglin/CD105 Quantikine ELISA Kit (36)
Citations are publications that use Bio-Techne products. Selected citations for Human Endoglin/CD105 Quantikine ELISA Kit include:
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Species: Human
Sample Types: Plasma
EO Anto et al. (2022), Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia PLoS ONE, 17(3):e0265717.
PMID: 35312727 -
Species: Human
Sample Types: Serum
A Abascal-Sa et al. (2022), The Relationship between Angiogenic Factors and Energy Metabolism in Preeclampsia Nutrients, 14(10).
PMID: 35631313 -
Species: Human
Sample Types: Cell Culture Supernates
L Ruiz-Llore et al. (2021), Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein International Journal of Molecular Sciences, 22(20).
PMID: 34681942 -
Species: Human
Sample Types: Whole Blood
I Nejmanová et al. (2021), High Soluble Endoglin Levels Affect Aortic Vascular Function during Mice Aging Journal of cardiovascular development and disease, 8(12).
PMID: 34940528 -
Species: Human
Sample Types: Serum
DL Wilson et al. (2020), Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy PLoS ONE, 15(4):e0232287.
PMID: 32339208 -
Species: Human
Sample Types: Cell Culture Supernates
E Gallardo-V et al. (2020), Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4 Cells, 9(4).
PMID: 32316263 -
Species: Human
Sample Types: Plasma
SP Polster et al. (2020), Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma Nat Commun, 11(1):2659.
PMID: 32461638 -
Species: Human
Sample Types: Placenta
RA Rahman et al. (2020), Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia Int J Mol Sci, 21(7).
PMID: 32260307 -
Species: Human
Sample Types: Plasma
L Pérez-Roqu et al. (2020), Pregnancy-Induced High Plasma Levels of Soluble Endoglin in Mice Lead to Preeclampsia Symptoms and Placental Abnormalities International Journal of Molecular Sciences, 22(1).
PMID: 33375253 -
Species: Human
Sample Types: Serum
S Kim et al. (2020), Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia Cells, 9(9).
PMID: 32878300 -
Species: Human
Sample Types: Plasma
HW Unger et al. (2019), Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection Sci Rep, 9(1):2260.
PMID: 30783215 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western BlotM Aristorena et al. (2019), MMP-12, Secreted by Pro-Inflammatory Macrophages, Targets Endoglin in Human Macrophages and Endothelial Cells Int J Mol Sci, 20(12).
PMID: 31242676 -
Species: Human
Sample Types: Plasma
H Li et al. (2018), LIFR increases the release of sEng via the up-regulation of MMP14 expression in PE Reproduction, 0(0).
PMID: 29363569 -
Species: Mouse
Sample Types: Plasma
L Ruiz-Remol et al. (2017), Circulating soluble endoglin modifies the inflammatory response in mice PLoS ONE, 12(11):e0188204.
PMID: 29145462 -
Species: Human
Sample Types: Serum
V Bláha et al. (2017), Lipoprotein apheresis in the treatment of dyslipidaemia - the Czech Republic experience Physiol Res, 66(0):S91-S100.
PMID: 28379034 -
Species: Human
Sample Types: Tissue Culture Supernates
M O'Brien et al. (2017), Endothelial Dysfunction in Severe Preeclampsia is Mediated by Soluble Factors, Rather than Extracellular Vesicles Sci Rep, 7(1):5887.
PMID: 28725005 -
Species: Human
Sample Types: Plasma
Yukihiko Momiyama (2016), Plasma Soluble Endoglin Levels Are Inversely Associated With the Severity of Coronary Atherosclerosis Arterioscler. Thromb. Vasc. Biol., 0(0).
PMID: 27789477 -
Species: Human
Sample Types: Tissue Homogenates
Ingrid C Weel (2016), Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia PLoS ONE, 11(6):e0157584.
PMID: 27315098 -
Species: Mouse
Sample Types: Plasma
Nemeckova I et al. (2015), High soluble endoglin levels do not induce endothelial dysfunction in mouse aorta. PLoS ONE, 10(3):e0119665.
PMID: 25768936 -
Species: Human
Sample Types: Serum
White W et al. (2014), Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury. PLoS ONE, 9(3):e92693.
PMID: 24664365 -
Species: Human
Sample Types: Plasma
Widemann B et al. (2012), A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report. Clin Cancer Res, 18(21):6011-22.
PMID: 22962440 -
Species: Human
Sample Types: Cell Culture Supernates
Kaitu'u-Lino TJ et al. (2012), MMP-15 Is Upregulated in Preeclampsia, but Does Not Cleave Endoglin to Produce Soluble Endoglin. PLoS ONE, 7(6):e39864.
PMID: 22768148 -
Species: Human
Sample Types: Plasma
Rana S et al. (2012), Plasma Concentrations of Soluble Endoglin versus Standard Evaluation in Patients with Suspected Preeclampsia. PLoS ONE, 7(10):e48259.
PMID: 23110221 -
Species: Human
Sample Types: Plasma
Silver KL et al. (2011), Circulating soluble endoglin levels in pregnant women in Cameroon and Malawi--associations with placental malaria and fetal growth restriction. PLoS ONE, 6(9):e24985.
PMID: 21966395 -
Species: Human
Sample Types: Plasma
Dubois SG et al. (2011), Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study. Clin. Cancer Res., 17(15):5113-22.
PMID: 21690570 -
Species: Human
Sample Types: Serum
Landt S et al. (2011), Prognostic significance of the angiogenic factors angiogenin, endoglin and endostatin in cervical cancer. Anticancer Res., 31(8):2651-5.
PMID: 21778318 -
Species: Human
Sample Types: Serum
Powers RW et al. (2010), Soluble fms-Like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies. PLoS ONE, 5(10):e13263.
PMID: 20948996 -
Species: Human
Sample Types: Serum
Jeyabalan A et al. (2010), Effect of smoking on circulating angiogenic factors in high risk pregnancies. PLoS ONE, 5(10):e13270.
PMID: 20967275 -
Species: Human
Sample Types: Serum
Santner-Nanan B et al. (2009), Systemic increase in the ratio between Foxp3+ and IL-17-producing CD4+ T cells in healthy pregnancy but not in preeclampsia. J. Immunol., 183(11):7023-30.
PMID: 19915051 -
Species: Human
Sample Types: Tissue Homogenates
Chen Y et al. (2009), Soluble endoglin modulates aberrant cerebral vascular remodeling. Ann. Neurol., 66(1):19-27.
PMID: 19670444 -
Species: Human
Sample Types: Plasma
Blankley RT et al. (2009), A proof-of-principle gel-free proteomics strategy for the identification of predictive biomarkers for the onset of pre-eclampsia. BJOG, 116(11):1473-80.
PMID: 19663911 -
Species: Human
Sample Types: Plasma
Shariat SF et al. (2008), Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers. Clin. Cancer Res., 14(12):3785-91.
PMID: 18559597 -
Species: Human
Sample Types: Plasma
Svatek RS et al. (2008), Preoperative plasma endoglin levels predict biochemical progression after radical prostatectomy. Clin. Cancer Res., 14(11):3362-6.
PMID: 18519764 -
Species: Human
Sample Types: Plasma
Karam JA et al. (2008), Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer. Clin. Cancer Res., 14(5):1418-22.
PMID: 18316564 -
Species: Human
Sample Types: Serum
Levine RJ et al. (2006), Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N. Engl. J. Med., 355(10):992-1005.
PMID: 16957146 -
Species: Human
Sample Types: Serum
Furstenberger G et al. (2006), Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br. J. Cancer, 94(4):524-31.
PMID: 16450002
There are no citations that match your criteria.
Customer Reviews for Human Endoglin/CD105 Quantikine ELISA Kit (1)
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Sample Tested: Plasma,UrineVerified Customer | Posted 11/08/2022Normal, healthy plasma was in range at 10-fold dilution and showed good linearity. Concentrations in normal, healthy urine were below the standard curve at 10-fold dilution so would recommend using a lower dilution factor.
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FAQs for Human Endoglin/CD105 Quantikine ELISA Kit
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Does this ELISA detect the L or S isoform of Endoglin?
Both isoforms are expected to be measured in this Endoglin ELISA. This assay recognizes the soluble, extracellular portion of the protein which is identical for the L & S isoforms. The differences between L & S Endoglin are located within the cytoplasmic region of the protein.
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Does this ELISA detect monomeric or dimeric Endoglin?
This assay is confirmed to measure dimeric soluble Endoglin. This assay has not been evaluated for reactivity with monomeric Endoglin.
Product Documents for Human Endoglin/CD105 Quantikine ELISA Kit
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.