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Endoglin/CD105: Antibodies

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

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359 results for "Endoglin/CD105 Primary Antibodies" in Products

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Endoglin/CD105: Antibodies

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

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359 results for "Endoglin/CD105 Primary Antibodies" in Products

WB, Simple Western, Flow, IHC, CyTOF-ready, ICC, KO
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
ELISA, ICC/IF, IHC, WB
WB, Flow, IHC, CyTOF-ready, ICC
WB, IHC, ICC
CyTOF-ready, Flow, ICC/IF, IHC, WB
WB, Flow, IHC
Flow, CyTOF-ready
Flow, ICC/IF, IHC, IP, WB
CyTOF-ready, Flow, IP, WB
WB, IHC, IP, ICC
Catalog #: MAB13201
WB
Flow
WB
Catalog #: FAB1320V
Flow
Catalog #: FAB10971U
Flow
Catalog #: FAB10971S
Flow
Flow, IHC, IP, WB

Clone SN6 was used by HLDA to establish CD designation.

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