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Endoglin/CD105: Antibodies

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

29 results for "Endoglin/CD105 Primary Antibodies" in Products

Endoglin/CD105: Antibodies

Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.

29 results for "Endoglin/CD105 Primary Antibodies" in Products

WB, IHC, IP, ICC
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC, KO
WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
Catalog #: FAB10971R
Flow
WB
WB, IHC, ICC
WB, Flow, IHC
WB, Flow, IHC, CyTOF-ready, ICC
Catalog #: BAM10971
Flow
Flow, CyTOF-ready
Flow
Catalog #: FAB1320N
Flow
Catalog #: FAB1320R
Flow
Catalog #: FAB1320G
Flow
Flow
Catalog #: FAB1320V
Flow
Catalog #: FAB10971T
Flow
Catalog #: FAB1320T
Flow
Catalog #: MAB13201
WB
Catalog #: FAB1320S
Flow
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