16 results for "EGFR" in Products
EGFR Products
EGFR (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. Ligand binding induces EGFR homodimerization as well as heterdimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ...
Highly potent EGFR-kinase inhibitor
Orally active, selective EGFR inhibitor
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
Potent, reversible EGFR tyrosine kinase inhibitor
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
Potent dual EGFR/ErbB2 inhibitor; orally active
Potent ErbB receptor family inhibitor
Potent ErbB receptor family inhibitor
Potent EGFR and VEGFR inhibitor
Potent EGFR kinase inhibitor
Potent irreversible pan ErbB inhibitor
Potent irreversible pan ErbB inhibitor
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor