
DNA Topoisomerase Inhibitors Products
14 results for "DNA Topoisomerase Inhibitors" in Products
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DNA Topoisomerase Inhibitors Products
14 results for "DNA Topoisomerase Inhibitors" in Products
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
Alternate Names : | Adriamycin, NSC 123127 |
Chemical Name : | 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione hydrochloride |
Purity : | ≥98% (HPLC) |
DNA topoisomerase I inhibitor; Camptothecin (Cat. No. 1100) analog
Alternate Names : | SK&F 104864-A |
Chemical Name : | 10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride |
Purity : | ≥98% (HPLC) |
Topoisomerase II inhibitor
Chemical Name : | [5R-[5α,5aβ,8aα,9β(R*)]]-9-[(4,6-Ο-Ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6-(5aH)-one |
Purity : | ≥99% (HPLC) |
DNA topoisomerase I inhibitor; antitumor
Alternate Names : | Irinotecan, Camptothecin 11 |
Chemical Name : | (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylic acid ester hydrochloride |
Purity : | ≥99% (HPLC) |
Topoisomerase II inhibitor; immunosuppressive and antineoplastic agent
Chemical Name : | 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride |
Purity : | ≥98% (HPLC) |
DNA topoisomerase inhibitor
Chemical Name : | (S)-4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
Purity : | ≥98% (HPLC) |
DNA topoisomerase I inhibitor; antitumor
Alternate Names : | 7-Ethyl-10-hydroxycamptothecin |
Chemical Name : | (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione |
Purity : | ≥98% (HPLC) |
Topoisomerase II inhibitor
Alternate Names : | ICRF-187 |
Chemical Name : | 4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride |
Purity : | ≥98% (HPLC) |
Prodrug topoisomerase II inhibitor
Alternate Names : | AQ4N |
Chemical Name : | 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride |
Purity : | ≥98% (HPLC) |
Antibiotic; inhibits bacterial DNA synthesis
Alternate Names : | CP 99219 |
Chemical Name : | 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate |
Purity : | ≥99% (HPLC) |
Inhibits TNF-α-induced NF-κB activation
Chemical Name : | (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid |
Purity : | ≥99% (HPLC) |
Cdk1 and cdk2 inhibitor
Chemical Name : | 6-(Cyclohexylmethoxy)-9H-purin-2-amine |
Purity : | ≥99% (HPLC) |
Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
Alternate Names : | 4'-Epidoxorubicin |
Chemical Name : | (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride |
Purity : | ≥96% (HPLC) |
DNA topoisomerase II inhibitor; viral transduction enhancer
Chemical Name : | (5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one |
Purity : | ≥98% (HPLC) |