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99 results for "COX-1" in Products

COX-1 Products

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

Cyclooxygenase inhibitor (COX-1 > COX-2)

Chemical Name: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole
Purity: ≥98% (HPLC)
Cyclooxygenase inhibitor (COX-1 > COX-2)

Cyclooxygenase-1 (COX-1) inhibitor

Chemical Name: 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Purity: ≥98% (HPLC)
Cyclooxygenase-1 (COX-1) inhibitor

Cyclooxygenase inhibitor; NSAID

Chemical Name: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt
Purity: ≥98% (HPLC)
Cyclooxygenase inhibitor; NSAID

Cyclooxygenase inhibitor

Chemical Name: 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol
Purity: ≥98% (HPLC)
Cyclooxygenase inhibitor

Cyclooxygenase inhibitor; NSAID

Chemical Name: 2-Acetoxybenzoic acid
Purity: ≥98% (HPLC)
Cyclooxygenase inhibitor; NSAID
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #345305
Reactivity: Human, Mouse
Details: Mouse IgG2b Monoclonal Clone #596002
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #345305
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #345305

Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6

Chemical Name: 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid
Purity: ≥98% (HPLC)
Calcium-activated chloride channel blocker;  NSAID. Also activates TRPC6
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #345305

Cyclooxygenase inhibitor; may be selective for COX-3

Alternate Names: Paracetamol
Chemical Name: N-(4-Hydroxyphenyl)acetamide
Purity: ≥98% (HPLC)
Cyclooxygenase inhibitor; may be selective for COX-3
Reactivity: Human
Details: Rat IgG2a Monoclonal Clone #345305
Reactivity: Human, Mouse
Details: Mouse IgG2b Monoclonal Clone #596002
Applications: ELISA
Reactivity: Human, Mouse
Details: Goat IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: COX-1 Antibody [NB100-867]
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