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8 results for "CHRM5 Small Molecules and Peptides" in Products

CHRM5: Small Molecules and Peptides

Muscarinic cholinergic receptor M5 is an Acetylcholine Receptor that is active during embryonic development. It is coupled to phosphoinositide degradation and to the activation of mitogen-activated protein kinase (MAPK). The M5 receptor has been reported to be expressed in blood, brain, and ovary. ESTs have been isolated from human testis and placenta libraries.

Functionally biased muscarinic M4 receptor agonist

Chemical Name: 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate
Purity: ≥98% (HPLC)
Functionally biased muscarinic M4 receptor agonist

Non-selective cholinergic agonist

Alternate Names: Carbachol
Chemical Name: (2-Hydroxyethyl)trimethylammonium chloride carbamate
Non-selective cholinergic agonist

Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist

Chemical Name: 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
Purity: ≥98% (HPLC)
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist

M5 receptor antagonist

Chemical Name: (3R,4S)-rel-1-[(2,3-Dihydro-5-benzofuranyl)sulfonyl]-3-fluoro-4-[[(1-methyl-1H-imidazol-2-yl)thio]methyl]piperidine
Purity: ≥98% (HPLC)
M5 Muscarinic Acetylcholine Receptor Antagonist

Muscarinic agonist

Chemical Name: 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate
Purity: ≥98% (HPLC)
Muscarinic agonist

Muscarinic agonist

Chemical Name: (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
Purity: ≥98% (HPLC)
Muscarinic agonist

Selective M1 muscarinic agonist

Chemical Name: 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride
Purity: ≥99% (HPLC)
Selective M1 muscarinic agonist

5-HT2A antagonist; also D2 antagonist; atypical antipsychotic

Chemical Name: 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
Purity: ≥98% (HPLC)
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
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