CD40/TNFRSF5 Products
CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.
992 results for "CD40/TNFRSF5" in Products
992 results for "CD40/TNFRSF5" in Products
CD40/TNFRSF5 Products
CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82111 |
| Applications: | Flow, AgAct, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, AgAct |
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #65924 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82102 |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | P25942-1 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #1C10 |
| Applications: | Flow, IP, AgAct, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #G28-5 |
| Applications: | IHC, ICC/IF, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1673 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82111 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | P27512 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #BLR056F |
| Applications: | IHC, WB, ICC/IF, IP, mIF |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82111 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #OTI8B8 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #OTI8B8 |
| Applications: | IHC, WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C40/1605 |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |