Cannabinoid R2/CB2/CNR2: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2 R.
15 results for "Cannabinoid R2/CB2/CNR2 Small Molecules and Peptides" in Products
15 results for "Cannabinoid R2/CB2/CNR2 Small Molecules and Peptides" in Products
Cannabinoid R2/CB2/CNR2: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2 R.
Selective high affinity CB2 agonist
| Alternate Names: | (R)-(+)-WIN 55212 |
| Chemical Name: | (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone mesylate |
| Purity: | ≥98% (HPLC) |
Selective CB2 inverse agonist
| Chemical Name: | 6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)methanone |
| Purity: | ≥98% (HPLC) |
Potent and selective CB2 agonist
| Chemical Name: | (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
| Purity: | ≥98% (HPLC) |
Endogenous and non-selective CB agonist; potent GPR55 agonist
| Alternate Names: | 2-AG,Arachidonoylglycerol |
| Chemical Name: | (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester |
Potent and selective CB2 agonist
| Chemical Name: | (1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol |
| Purity: | ≥98% (HPLC) |
CB2 receptor inverse agonist
| Chemical Name: | N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Cannabinoid receptor partial agonist
| Chemical Name: | 2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol |
| Purity: | ≥95% (HPLC) |
Endogenous and non-selective CB agonist
| Alternate Names: | Arachidonylethanolamide,AEA |
| Chemical Name: | N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Purity: | ≥98% (HPLC) |
Selective CB2 receptor inverse agonist
| Chemical Name: | N-(1,3-Benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-quinolinecarboxamide |
| Purity: | ≥98% (HPLC) |
Selective GPR55 agonist. FAAH and PAA substrate
| Alternate Names: | PEA |
| Chemical Name: | N-(2-Hydroxyethyl)hexadecanamide |
Potent and selective CB2 partial agonist; orally biovailable
| Chemical Name: | 3-Cyclopropyl-1-[[4-[6-[(1,1-dioxido-4-thiomorpholinyl)methyl]-5-fluoro-2-pyridinyl]phenyl]methyl]-2,4-imidazolidinedione hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity, selective CB2 agonist
| Chemical Name: | N-Cyclohexyl-7-chloro-1-[2-(4-morpholinyl)ethyl]quinolin-4(1H)-one-3-carboxamide |
| Purity: | ≥99% (HPLC) |
Highly potent and selective CB2 inverse agonist
| Chemical Name: | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of CB2 receptors; active in vivo
| Chemical Name: | N-[5-Bromo-1-[(4-fluorophenyl)methyl]-1,2-dihydro-4-methyl-2-oxo-3-pyridinyl]cycloheptanecarboxamide |
| Purity: | ≥98% (HPLC) |
Highly potent and selective CB2R agonist
| Chemical Name: | N-[(3E)-5-tert-Butyl-2-(cyclobutylmethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-ylidene]-2-(2-hydroxy-2-methylpropoxy)-5-(trifluoromethyl)benzamide |
| Purity: | ≥97% (HPLC) |
