beta-3 Adrenergic R/ADRB3: Small Molecules and Peptides
ADRB3 belongs to the G protein coupled-receptor 1 family of beta adrenergic receptors. Beta-adrenergic receptors, including ADRB3, mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. ADRB3 is involved in the regulation of lipolysis and thermogenesis. A variant of ADRB3 seems to be associated with weight gain (obesity). ADRB3 is also associated with susceptibility to non-insulin-dependent diabetes mellitus.
12 results for "beta-3 Adrenergic R/ADRB3 Small Molecules and Peptides" in Products
12 results for "beta-3 Adrenergic R/ADRB3 Small Molecules and Peptides" in Products
beta-3 Adrenergic R/ADRB3: Small Molecules and Peptides
ADRB3 belongs to the G protein coupled-receptor 1 family of beta adrenergic receptors. Beta-adrenergic receptors, including ADRB3, mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. ADRB3 is involved in the regulation of lipolysis and thermogenesis. A variant of ADRB3 seems to be associated with weight gain (obesity). ADRB3 is also associated with susceptibility to non-insulin-dependent diabetes mellitus.
Highly selective β3 agonist
| Chemical Name: | 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid disodium salt |
| Purity: | ≥97% (HPLC) |
Standard selective β agonist
| Alternate Names: | Isoprenaline |
| Chemical Name: | 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective β3 agonist
| Chemical Name: | 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
β antagonist
| Chemical Name: | (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% (HPLC) |
β3 agonist
| Chemical Name: | (R*,R*)-(±)-4-[2-[(2-(3-Chlorophenyl)-2-hydroxyethyl)amino]propyl]phenoxyacetic acid, sodium salt |
| Purity: | ≥98% (HPLC) |
Potent and selective β3 antagonist
| Chemical Name: | 1-(2-Ethylphenoxy)-3-[[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]-(2S)-2-propanol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and non-selective β antagonist; also potent α1 antagonist
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% (HPLC) |
β3 partial agonist. β1/β2 antagonist
| Chemical Name: | 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride |
Selective β3 antagonist
| Chemical Name: | N-[[3-[(2S)-2-Hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl]-acetamide |
| Purity: | ≥98% (HPLC) |
β3 agonist; displays anxiolytic and antidepressant effects
| Chemical Name: | [[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]ox]yacetic acid ethyl ester hydrochloride |
| Purity: | ≥98% (HPLC) |
