Isoproterenol hydrochloride
Catalog # 1747 | Tocris Bioscience a Bio-Techne Brand
Standard selective β agonist
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Key Product Details
Description: | Standard selective β agonist |
Alternative Names: | Isoprenaline |
Chemical Name: | 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 247.72 |
Citations for Isoproterenol hydrochloride (27)
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Citations are publications that use Bio-Techne products. Selected citations for Isoproterenol hydrochloride include:
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Turkieh et al.
(2019)
Increased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity.
Cell Death Dis.
10:608
PMID: 31406108 -
Rudnicki et al.
(2018)
Female Mice Have Higher Angiogenesis in Perigonadal Adipose Tissue Than Males in Response to High-Fat Diet.
Front Physiol.
9:1452
PMID: 30405427 -
McKeithan et al.
(2017)
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes.
Front Physiol.
8:766
PMID: 29075196 -
Komolov et al.
(2017)
Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5.
Cell.
169:407
PMID: 28431242 -
Hernández-Cascales
(2017)
Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium.
PeerJ.
5:e3113
PMID: 28382232 -
Liu et al.
(2016)
DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH.
FASEB J.
30:635
PMID: 26481310 -
Stoddart et al.
(2015)
Application of BRET to monitor ligand binding to GPCRs.
Nat Methods.
12:661
PMID: 26030448 -
Sun et al.
(2015)
Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling.
Nat Commun.
5:15950
PMID: 26516061 -
Siuda et al.
(2015)
Optodynamic simulation of β-adrenergic receptor signalling.
Circ Arrhythm Electrophysiol.
6:8480
PMID: 26412387 -
Lang et al.
(2015)
Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart.
Cereb Cortex.
8:409
PMID: 25673629 -
Merino et al.
(2015)
Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with isoprote.
J Mol Cell Cardiol.
10:e0132884
PMID: 26222156 -
Hansen and Manahan-Vaughan
(2015)
Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors.
Eur J Neurosci.
25:1889
PMID: 24464942 -
Gray et al.
(2014)
Inhibitory interactions between phosphorylation sites in the C terminus of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor GluA1 subunits.
Biochem Biophys Res Commun.
289:14600
PMID: 24706758 -
Yang et al.
(2014)
PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling.
Diabetes.
66:83
PMID: 24225179 -
Williams et al.
(2014)
Excitatory drive onto DArgic neurons in the rostral linear nucleus is enhanced by NE in an α1 adrenergic receptor-dependent manner.
Neuropharmacology.
86:116
PMID: 25018040 -
Zhang et al.
(2013)
NE drives persistent activity in prefrontal cortex via synergistic α1 and α2 adrenoceptors.
PLoS One.
8:e66122
PMID: 23785477 -
Zaytseva et al.
(2013)
Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion.
Sens Actuators B Chem.
188
PMID: 24319319 -
Silberman and Winder
(2013)
Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala.
Neuropharmacology.
70:316
PMID: 23470280 -
Santulli et al.
(2012)
Age-related impairment in Ins release: the essential role of β(2)-adrenergic receptor.
J Cell Biol.
61:692
PMID: 22315324 -
Zemkova et al.
(2011)
NE causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+.
Endocrinology.
152:3842
PMID: 21828176 -
Rankovic et al.
(2011)
Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.
PLoS One.
6:e27474
PMID: 22164209 -
Chigaev et al.
(2011)
Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.
J Biol Chem.
286:20375
PMID: 21515675 -
Nobis et al.
(2011)
β-Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism.
Biol Psychiatry.
69:1083
PMID: 21334600 -
Duncan et al.
(2010)
The effects of aging and chronic fluox. treatment on circadian rhythms and suprachiasmatic nucleus expression of neuropeptide genes and 5-HT1B receptors.
J Biol Chem.
31:1646
PMID: 20525077 -
Clark et al.
(2010)
Reversibly sealed multilayer microfluidic device for integrated cell perfusion and on-line chemical analysis of cultured adipocyte secretions.
Anal Bioanal Chem.
397:2939
PMID: 20549489 -
Maehashi et al.
(2008)
Bitter peptides activate hTAS2Rs, the human bitter receptors.
PLoS One.
365:851
PMID: 18037373 -
Cardin and Schmidt
(2004)
Noradrenergic inputs mediate state dependence of auditory responses in the avian song system.
Sci Rep.
24:7745
PMID: 15342742
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Customer Reviews for Isoproterenol hydrochloride (4)
4.8 out of 5
4 customer ratings
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Species: HumanCell Line/Tissue: sh-sy5yUsed it in Mg image experiment, and it can induce obvious Mg influx.
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Species: HumanAssay Type: In VitroCell Line/Tissue: HEK293HEK293 cells transfected with cAMP FRET sensor, Epac-S(H187) were perfused in normal tyrode solution and excited alternately at 430 nm and fluorescence was captured at 470 and 535 nm. Isoprenaline (10 µM) was added at 1 min to elevate intracellular cAMP, which is detected as an increase in 470/535 fluorescence ratio.
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Species: HumanLive assay treatment
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Species: MouseAssay Type: In VivoWe used this product to treat ARKO mice to investigate the cell signalling pathway
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