alpha-Fetoprotein/AFP Products
alpha-Fetoprotein (AFP), is albuminoid superfamily protein that is synthesized in the fetus primarily by the liver, yolk sac, and tissues of gastrointestinal origin. It is one of the earliest markers of the hepatocyte lineage. AFP acts as a carrier protein for steroids, bilirubin, fatty acids, retinoids, and flavonoids. In addition, it can exert immunosuppressive activity, regulate cell proliferation and apoptosis, initiate intracellular signaling, and contribute to cell invasion. Altered levels of both fetal and maternal AFP have been associated with hypothyroidism, autoimmune disorders, and heart defects. Low maternal serum AFP levels are associated with a higher incidence of Down syndrome, whereas higher levels are associated with spina bifida and anencephaly. Elevated AFP levels are also coincident with liver, stomach, and germ cell cancers.
715 results for "alpha-Fetoprotein/AFP" in Products
715 results for "alpha-Fetoprotein/AFP" in Products
alpha-Fetoprotein/AFP Products
alpha-Fetoprotein (AFP), is albuminoid superfamily protein that is synthesized in the fetus primarily by the liver, yolk sac, and tissues of gastrointestinal origin. It is one of the earliest markers of the hepatocyte lineage. AFP acts as a carrier protein for steroids, bilirubin, fatty acids, retinoids, and flavonoids. In addition, it can exert immunosuppressive activity, regulate cell proliferation and apoptosis, initiate intracellular signaling, and contribute to cell invasion. Altered levels of both fetal and maternal AFP have been associated with hypothyroidism, autoimmune disorders, and heart defects. Low maternal serum AFP levels are associated with a higher incidence of Down syndrome, whereas higher levels are associated with spina bifida and anencephaly. Elevated AFP levels are also coincident with liver, stomach, and germ cell cancers.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #189502 |
| Applications: | WB, Simple Western, CyTOF-ready, ICC, ICFlow, +1 More |
| Sensitivity: | 0.029 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #AFP/7007R |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: alpha-Fetoprotein/AFP Antibody (AFP/7007R) [NBP3-13870]](https://resources.bio-techne.com/images/products/alpha-Fetoprotein-AFP-Antibody-AFP-7007R-Immunohistochemistry-Paraffin-NBP3-13870-img0001.jpg "Immunohistochemistry-Paraffin: alpha-Fetoprotein/AFP Antibody (AFP/7007R) [NBP3-13870]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #189506 |
| Applications: | CyTOF-reported, ICC, ICFlow, KO |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #AFP/7007R |
| Applications: | IHC |
![alpha-Fetoprotein/AFP Antibody (AFP/7007R) - Azide and BSA Free Immunohistochemistry-Paraffin: alpha-Fetoprotein/AFP Antibody (AFP/7007R) - Azide and BSA Free [NBP3-14053] -](https://resources.bio-techne.com/images/products/nbp3-14053_rabbit-alpha-fetoprotein-afp-mab-afp-7007r-azide-bsa-free-24120258211635.jpg "Immunohistochemistry-Paraffin: alpha-Fetoprotein/AFP Antibody (AFP/7007R) - Azide and BSA Free [NBP3-14053] -")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #AFP/7007R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #AFP/7007R |
| Applications: | IHC |
![alpha-Fetoprotein/AFP Antibody (AFP/7007R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-14053cl1_rabbit-alpha-fetoprotein-afp-mab-afp-7007r-corafluor-1-299202515215713.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #AFP/7007R |
| Applications: | IHC |
| Reactivity: | Human, Rat |
| Details: | Chicken IgY Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC, KO |
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human, Porcine |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1G7 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP, +1 More |
![Western Blot: alpha-Fetoprotein/AFP Antibody (1G7) [H00000174-M01]](https://resources.bio-techne.com/images/products/alpha-Fetoprotein-AFP-Antibody-1G7-Western-Blot-H00000174-M01-img0018.jpg "Western Blot: alpha-Fetoprotein/AFP Antibody (1G7) [H00000174-M01]")
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Func |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #189502 |
| Applications: | ICFlow, KO |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #214107 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #214107 |
| Applications: | WB |
| Reactivity: | Human, Canine, Monkey, Primate |
| Details: | Mouse IgG2B Monoclonal Clone #OTI2A9 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: alpha-Fetoprotein/AFP Antibody (OTI2A9) [NBP2-03084]](https://resources.bio-techne.com/images/products/alpha-Fetoprotein-AFP-Antibody-OTI2A9-Western-Blot-NBP2-03084-img0006.jpg "Western Blot: alpha-Fetoprotein/AFP Antibody (OTI2A9) [NBP2-03084]")
| Reactivity: | Human, Canine, Monkey, Primate |
| Details: | Mouse IgG2B Monoclonal Clone #OTI2A9 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
![Western Blot: alpha-Fetoprotein/AFP Antibody (OTI2A9)Azide and BSA Free [NBP2-70103]](https://resources.bio-techne.com/images/products/alpha-Fetoprotein-AFP-Antibody-OTI2A9-Azide-and-BSA-Free-Western-Blot-NBP2-70103-img0002.jpg "Western Blot: alpha-Fetoprotein/AFP Antibody (OTI2A9)Azide and BSA Free [NBP2-70103]")
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #214107 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #189508 |
| Applications: | WB, KO, Simple Western |
![Knockout Validated: alpha-Fetoprotein/AFP Antibody (189508) [MAB13692]](https://resources.bio-techne.com/images/products/alpha-Fetoprotein-AFP-Antibody-189508-Knockout-Validated-MAB13692-img0005.jpg "Knockout Validated: alpha-Fetoprotein/AFP Antibody (189508) [MAB13692]")