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4-1BB/TNFRSF9/CD137: Antibodies

4-1BB, also known as CD137 and TNFRSF9, is a transmembrane TNF receptor superfamily member that is expressed as on various populations of activated T cell including CD4+, CD8+, memory CD8+, NKT, and regulatory T cells as well as on myeloid and mast cell progenitors, dendritic cells, mast cells, and bacterially infected osteoblasts. 4-1BB binding by 4-1BB Ligand costimulates T cell proliferation, activation, and/or survival and can enhance the activation-induced cell death of repetitively stimulated T cells. 4-1BB can associate with OX40 on activated T cells, forming a complex that responds to either ligand and inhibits Treg and CD8+ T cell proliferation. Reverse signaling through 4-1BB Ligand inhibits the development of dendritic cells, B cells, and osteoclasts but supports mature dendritic cell survival and costimulates the proliferation and activation of mast cells.

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271 results for "4-1BB/TNFRSF9/CD137 Primary Antibodies" in Products

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4-1BB/TNFRSF9/CD137: Antibodies

4-1BB, also known as CD137 and TNFRSF9, is a transmembrane TNF receptor superfamily member that is expressed as on various populations of activated T cell including CD4+, CD8+, memory CD8+, NKT, and regulatory T cells as well as on myeloid and mast cell progenitors, dendritic cells, mast cells, and bacterially infected osteoblasts. 4-1BB binding by 4-1BB Ligand costimulates T cell proliferation, activation, and/or survival and can enhance the activation-induced cell death of repetitively stimulated T cells. 4-1BB can associate with OX40 on activated T cells, forming a complex that responds to either ligand and inhibits Treg and CD8+ T cell proliferation. Reverse signaling through 4-1BB Ligand inhibits the development of dendritic cells, B cells, and osteoclasts but supports mature dendritic cell survival and costimulates the proliferation and activation of mast cells.

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271 results for "4-1BB/TNFRSF9/CD137 Primary Antibodies" in Products

WB, Flow, IHC, AgAct, CyTOF-ready
WB, Simple Western, Flow, IHC, AgAct, CyTOF-ready, ICC
WB, Flow, CyTOF-ready
WB, Simple Western, Flow, CyTOF-ready, ICC

Recombinant Monoclonal Antibody.

Catalog #: BAF937
WB, Flow
WB, Flow, ICC
Flow, AgAct, CyTOF-ready

Recombinant Monoclonal Antibody.

Flow
Catalog #: MAB9372
WB, Block
WB, Flow, CyTOF-ready
Flow, CyTOF-ready, ICC
Catalog #: FAB937R
Flow
Catalog #: FAB8382G
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB8382R
Flow

Recombinant Monoclonal Antibody.

Catalog #: MAB9372R
Block

Recombinant Monoclonal Antibody.

Catalog #: FAB838G
Flow
Catalog #: FAB838U
Flow
Catalog #: FAB838N
Flow
Catalog #: FAB838S
Flow
Catalog #: FAB838V
Flow
Catalog #: FAB838T
Flow
Catalog #: FAB838R
Flow
Catalog #: FAB937G
Flow
Catalog #: FAB937N
Flow
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