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NMDA Receptor Antagonists Small Molecule

Key Product Details

Description: Potent and selective NMDA receptor antagonist; more active form of DL-AP5
Alternative Names: 2-APV, D-APV, D-2-amino-5-phosphonovalerate
Chemical Name: D-(-)-2-Amino-5-phosphonopentanoic acid
Purity: ≥99% (HPLC)

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Citations (372)

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Customer Reviews

4.3 out of 5
7 customer ratings
5 stars
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4 stars
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  • Neuron glia culture
    Name: Anonymous | 12th Jul 2020
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Mixed neuron-glia
    D-AP5 (100 μM)
    Incubate for 24h
    Neuron glia culture Serum 0106
  • Validation
    Name: Anonymous | 4th Apr 2020
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Sprague-Dawley rats primary neuronal
    10 μM for 2 h
    Validation Serum 0106
  • Antidepressantsby Cholecystokinin Neurons of the Dentate Gyrus
    Name: Anonymous | 3rd Feb 2020
    Species: Mouse
    Assay Type: In Vivo
    10uM D-AP5
    Antidepressantsby Cholecystokinin Neurons of the Dentate Gyrus Serum 0106
  • Works as intended
    Name: Anonymous | 14th May 2019
    Species: Mouse
    Assay Type: In Vivo
    We delivered this drug intracranially in combination with DNQX to block glutamatergic transmission in the mouse VTA. Product was highly soluble and worked well and as described, producing a robust decrease in place preference behavior.
  • Validation
    Name: Kevin Xu | 4th Jan 2018
    Species: Mouse
    Cell Line/Tissue: Lung
    Good reproducibility
  • product review
    Name: Harika Vemula | 4th Jan 2018
    Species: Rat
    Assay Type: In Vivo
    in in-vivo studies
  • NMDA antagonist
    Name: Anonymous | 17th Jul 2017
    Species: Mouse
    Assay Type: In Vivo
    NMDA antagonist

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