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NMDA Receptor Antagonists Small Molecule
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0106/1
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Key Product Details

Description: Potent and selective NMDA receptor antagonist; more active form of DL-AP5
Alternative Names: 2-APV, D-APV, D-2-amino-5-phosphonovalerate
Chemical Name: D-(-)-2-Amino-5-phosphonopentanoic acid
Purity: ≥99% (HPLC)
Molecular Weight: 197.13

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Citations (372)

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Customer Reviews (6)

4.3 out of 5
6 customer ratings
5 stars
33%
4 stars
67%
3 stars
0%
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  • Neuron glia culture
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Mixed neuron-glia
    D-AP5 (100 μM)
    Incubate for 24h
    D-AP5 Serum 0106
  • Validation
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Sprague-Dawley rats primary neuronal
    10 μM for 2 h
    D-AP5 Serum 0106
  • Antidepressantsby Cholecystokinin Neurons of the Dentate Gyrus
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    10uM D-AP5
    D-AP5 Serum 0106
  • Works as intended
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    We delivered this drug intracranially in combination with DNQX to block glutamatergic transmission in the mouse VTA. Product was highly soluble and worked well and as described, producing a robust decrease in place preference behavior.
  • Validation
    Name: Kevin Xu
    Species: Mouse
    Cell Line/Tissue: Lung
    Good reproducibility
  • product review
    Name: Harika Vemula
    Species: Rat
    Assay Type: In Vivo
    in in-vivo studies

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Product Documents

Certificate of Analysis

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