Key Product Details
Description: | Potent and selective NMDA antagonist; less active form of DL-AP5 |
Chemical Name: | L-(+)-2-Amino-5-phosphonopentanoic acid |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 197.13 |
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Citations for L-AP5 (3)
Citations are publications that use Bio-Techne products. Selected citations for L-AP5 include:
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Fan et al.
(2016)
Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice.
Front Cell Neurosci.
10:74
PMID: 27047338 -
Kinney
(2005)
GAT-3 transporters regulate inhibition in the neocortex.
J Neurophysiol.
94:4533
PMID: 16135550 -
Fernández-Monreal et al.
(2004)
Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-MthD.-aspartate receptor signaling.
J Biol Chem.
279:50850
PMID: 15448144
There are no citations that match your criteria.
Customer Reviews for L-AP5 (1)
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Species: MouseAssay Type: In VivoCell Line/Tissue: BrainAP5 is an NMDA antagonist, so we have used it to block the function of neurons. Neuronal activity of animals injected with AP5 into the brain were decreased, seen as low expression of the protein CFOS.
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